| Description |
1 online resource (xvi, 380 pages) : illustrations (some color) |
| Contents |
Ch. 1. Small molecules for chemogenomics-based drug discovery / Edgar Jacoby [and others] -- ch. 2. Mapping the chemogenomic space / Jordi Mestres -- ch. 3. Natural product scaffolds and Protein Structure Similarity Clustering (PSSC) as inspiration sources for compound library design in chemogenomics and drug development / Frank J. Dekker, Stefan Wetzel and Herbert Waldmann -- ch. 4. A reductionist approach to chemogenomics in the design of drug molecules and focused libraries / Roger Crossley and Martin Slater -- ch. 5. In silico screening of the protein structure repertoire and of protein families / Didier Rognan -- ch. 6. New methods for similarity-based virtual screening / Jérôme Hert, Peter Willett and David J. Wilton -- ch. 7. Structural informatics: chemogenomics In silico / Derek A. Debe, Kevin P. Hambly and Joseph F. Danzer -- ch. 8. Construction of a homogeneous and informative In vitro profiling database for anticipating the clinical effects of drugs / Nicholas Froloff [and others] |
| Summary |
Devoted to the subject of shape charge design using numerical methods, this book offers the defense and commercial industries unique material not contained in any other single volume. The coverage of the Lagrangian and Eulerian methods as well as the equation of state provides first hand help to engineers working on shape charge problems. The book includes detailed descriptions of oil-well perforation not available from any other sources and, coupled with the material flow physics discussed in Chapters 2 and 3 and Appendix B, readers can design the fuel rod configurations for a nuclear reactor core. The equations of state and the constitutive models in Chapter 8 are among the best material models currently available |
| Bibliography |
Includes bibliographical references and indexes |
| Notes |
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL |
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Print version record |
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digitized 2011 HathiTrust Digital Library committed to preserve pda MiAaHDL |
| Subject |
Shaped charges -- Computer simulation
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Shaped charges -- Mathematical models
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Flow visualization -- Computer simulation
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Penetration mechanics -- Computer simulation
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Lagrange equations.
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TECHNOLOGY & ENGINEERING -- Military Science.
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Lagrange equations
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Penetration mechanics -- Computer simulation
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Shaped charges -- Mathematical models
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| Form |
Electronic book
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| Author |
World Scientific (Firm)
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| ISBN |
9789812707130 |
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9812707131 |
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