Title Biochemical targets of plant bioactive compounds : a pharmacological reference guide to sites of action and biological effects / Gideon Polya

Published London ; New York : Taylor & Francis, 2003

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Description 1 online resource (xii, 847 pages) : illustrations Contents Plant defensive compounds and their biochemical targets -- Introduction -- Organization and scope of the book -- Description of the tables -- Using the tables -- The structural diversity of plant defensive compounds -- Plant alkaloids -- Plant phenolics -- Plant terpenes -- Other plant compounds -- Biochemistry: the chemistry of life -- Introduction: water-based life -- Protein structure -- Enzymes and ligand-binding proteins -- Metabolic strategies -- Inhibition of biochemical processes by plant defensive compounds -- Neurotransmitter- and hormone-gated ion channels -- Introduction: electrical signalling in excitable cells -- Ionotropic neurotransmitter receptors: neurotransmitter-gated ion channels -- Structure and function of ionotropic receptors -- Ion pumps, ligand- and voltage-gated ion channels -- Introduction -- Ion pumps -- Voltage-gated Na channels -- Ligand-regulated and voltage-gated K channels -- Voltage-gated Ca²⁺ channels -- Ligand-gated Ca²⁺ channels -- Chloride transport and voltage-regulated chloride channels Summary When introduced to the human body, bioactive metabolites produced by plants for self defense bind to particular biochemical targets, most notably to proteins involved in signaling by hormones and neurotransmitters. This, essentially, is the basis for the effects of herbal medicine. While herbal medicine preparations may act by complex synergistic interactions, molecular explanations of herbal medicine efficacy and side effects ultimately require definition of the biochemical targets of individual plant bioactive constituents. Biochemical Targets of Plant Bioactive Compounds is a comprehensive Bibliography Includes bibliographical references and indexes Subject Botanical chemistry -- Handbooks, manuals, etc Materia medica, Vegetable -- Handbooks, manuals, etc Pharmacognosy -- Handbooks, manuals, etc Plant products -- Handbooks, manuals, etc Plants -- Metabolism -- Handbooks, manuals, etc Pharmacognosy. Cellular signal transduction. Structure-activity relationships (Biochemistry) Plant Extracts -- metabolism Pharmacognosy Signal Transduction Structure-Activity Relationship MEDICAL -- Pharmacology. Materia medica, Vegetable. Botanical chemistry. Plant products. Pharmacognosy. Plants -- Metabolism. Plant Extracts -- metabolism. Biological Factors. Signal Transduction. Structure-Activity Relationship. Structure-activity relationships (Biochemistry) Cellular signal transduction Botanical chemistry Materia medica, Vegetable Pharmacognosy Plant products Plants -- Metabolism Genre/Form handbooks. Handbooks and manuals Handbooks and manuals. Guides et manuels. Form Electronic book LC no. 2002155281 ISBN 0415308291 9780415308298 0203013719 9780203013717 9781420023527 1420023527 1280103310 9781280103315 9780429214981 0429214987

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