| Description |
1 online resource (1 PDF file (viii, 90 pages) : illustrations |
| Series |
Integrated systems physiology : from molecules to function to disease ; #9 |
|
Colloquium series on integrated systems physiology ; #9. 2154-5626
|
| Contents |
Introduction -- Placental blood circulation -- Maternal-placental blood circulation -- Fetal-placental circulation -- Structure of the placenta -- Cell types of the placenta -- Cytotrophoblasts and syncytiotrophoblasts -- Villous core stroma cells -- Pericytes/endothelial cells -- Oxygen tension and placental vascular development -- Oxygen tension and establishment of maternal-placental circulation -- Hypoxia and trophoblast differentiation -- Models of placental hypoxia -- Vasculogenesis and angiogenesis of human placenta -- Angiogenic factors -- VEGF family molecules and VEGF receptors -- FGFs and FGF receptors -- Angiopoietins and tie system -- Vasoactivators and placental vasoactivity -- Renin-angiotensin system -- Arachidonic acid metabolites: thromboxane and prostacyclin -- Endothelin-1 and its receptors -- Nitric oxide -- Chymase -- Role of trophoblasts in regulation of placental vasoactivity -- Lymphatic phenotypic characteristics of the human placenta -- Placental tissue and cord blood stem cells |
| Summary |
The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta |
| Analysis |
placenta circulation |
|
trophoblast |
|
angiogenesis |
|
vasoactivity |
|
placental stem cells |
| Bibliography |
Includes bibliographical references |
| Subject |
Placenta -- Blood-vessels
|
|
Placental Circulation -- physiology
|
|
Trophoblasts -- physiology
|
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Fetal Stem Cells -- physiology
|
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Receptors, Vascular Endothelial Growth Factor -- physiology
|
|
HEALTH & FITNESS -- Pregnancy & Childbirth.
|
|
Placenta -- Blood-vessels
|
| Form |
Electronic book
|
| Author |
Zhao, Shuang, MD.
|
| ISBN |
9781615040452 |
|
1615040455 |
|
9781615040469 |
|
1615040463 |
|
