| Description |
1 online resource (xiii, 333 pages : illustrations) |
| Series |
Advances in botanical research ; v. 76 |
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Advances in botanical research ; v. 76.
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| Contents |
Front Cover; ADVANCES IN BOTANICAL RESEARCH; Plant Cyclotides; Copyright; Contents; CONTRIBUTORS; PREFACE; One -- Overview on the Discovery and Applications of Cyclotides; 1. INTRODUCTION; ACKNOWLEDGMENTS; REFERENCES; Two -- Cyclotides in the Violaceae; 1. THE DISCOVERY OF CYCLOTIDES IN VIOLACEAE; 2. UNLOCKING THE CYCLOTIDE LIBRARY; 3. THE VIOLACEAE; 4. VIOLACEAE-THE PHARMACOPOEIA; 5. GROWING NEEDS AND SOURCES OF CYCLOTIDES; 6. COMPLETING THE CIRCLE; ACKNOWLEDGMENTS; REFERENCES; Three -- Cyclotides in the Rubiaceae; 1. INTRODUCTION; 2. DISCOVERY OF CYCLOTIDES |
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2.1 Cyclotide Analytical Screening Workflow2.2 Cyclotides Sequence Analysis Using Transcriptomics and Peptidomics; 3. DISTRIBUTION OF CYCLOTIDES IN RUBIACEAE; 3.1 Rubiaceae-An Overview; 3.2 Morphology and Taxonomy of Rubiaceae; 3.3 Distribution of Cyclotides within Rubiaceae; 3.4 Cyclotide Precursors of Rubiaceae Plants; 3.5 Cyclotide Sequence Variations within Rubiaceae; 3.6 Distribution of Cyclotides in Other Gentianales; 4. EVOLUTION OF CYCLOTIDES; 5. BIOACTIVITIES OF RUBIACEAE CYCLOTIDES; 6. CONCLUSION AND OUTLOOK; ACKNOWLEDGMENTS; REFERENCES; Four -- Cyclotides from Chinese Plants |
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1. Introduction2. Chemical Detection Method for Cyclotides; 3. Distribution and Chemotaxonomy of Cyclotides in Chinese Plants; 4. Extraction, Isolation and Structural Elucidation of Cyclotides in Chinese Plants; 4.1 Extraction and Isolation of Cyclotides in Chinese Plants; 4.2 Tandem MS Sequencing of Cyclotides in Chinese Plants; 4.3 NMR Characterization of Cyclotides in Chinese Plants; 5. Biological Activity of Cyclotides in Chinese Plants; Acknowledgments; References; Five -- Primary Structural Analysis of Cyclotides; 1. CYCLOTIDE DISCOVERY-UNTANGLING THE CYSTINE KNOT |
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2. TOOLS FOR PEPTIDE SEQUENCE ASSIGNMENT2.1 Gene Sequencing; 2.2 Genome Mining; 2.3 Next-Generation Sequencing; 2.4 Peptide Extraction and Purification; 2.5 Acid Hydrolysis and Amino Acid Analysis; 2.6 Edman Degradation; 2.7 Chemical and Enzymatic Digestion; 3. MASS SPECTROMETRY; 3.1 Ionization; 3.1.1 Electrospray Ionization; 3.1.2 Nanoelectrospray Ionization; 3.1.3 Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry; 3.2 Mass Analyzers; 3.2.1 Quadrupole Mass Analyzers; 3.2.2 TOF Mass Analyzers; 3.3 Peptide Sequencing; 4. APPLICATION OF MASS SPECTROMETRY TO CYCLOTIDE SEQUENCING |
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4.1 MS Analysis of Cyclotides4.2 Tandem Mass Spectrometric (MS/MS) Analysis of Cyclotides; 4.3 Application of "Omics" Technologies to Cyclotide Sequencing; 5. CHALLENGES AND COMPLEXITIES; 5.1 Co-eluting, Isobaric Peptides; 5.2 N/D Isoforms; 5.3 Unknown Genomes/Incomplete DBs; 6. FUTURE PROSPECTS; 6.1 Transcriptomics and Bioinformatics; 6.2 Automation and Robotics; 6.3 Advances in MS Hardware; 6.4 Advances in MS Software; 7. CONCLUDING REMARKS; REFERENCES; Six -- Structural Studies of Cyclotides; 1. THE CYCLIC CYSTINE KNOT; 2. STRUCTURAL FEATURES OF CYCLOTIDES; 2.1 Structural Studies |
| Analysis |
cyclische peptiden |
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cyclic peptides |
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peptiden |
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peptides |
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geneeskrachtige kruiden |
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herbal drugs |
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violaceae |
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rubiaceae |
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traditionele chinese geneeskunde |
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traditional chinese medicine |
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traditionele geneeskunde |
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traditional medicine |
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Plant Biotechnology |
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Organic Chemistry |
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Plantenbiotechnologie |
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Organische chemie |
| Bibliography |
Includes bibliographical references and indexes |
| Notes |
Text in English |
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CIP data; item not viewed |
| Subject |
Cyclic peptides.
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Plant bioactive compounds.
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Plant defenses.
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Peptides, Cyclic
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SCIENCE -- Life Sciences -- Biochemistry.
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Cyclic peptides.
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Plant bioactive compounds.
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Plant defenses.
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| Form |
Electronic book
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| Author |
Craik, David James, editor.
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| ISBN |
9780128007976 |
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0128007974 |
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