Description |
1 online resource (xiv, 331 pages) : illustrations |
Series |
Methods in molecular biology, 1064-3745 ; 444 |
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Methods in molecular biology (Clifton, N.J.) ; v. 444
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Contents |
Spectral Karyotyping (SKY): Applications in Prenatal Diagnostics / S. Mergenthaler-Gatfield, W. Holzgreve and S. Hahn -- Characterization of prenatally assessed de novo small supernumerary marker chromosomes by molecular cytogenetics / T. Liehr -- Rapid Prenatal Aneuploidy Screening by Fluorescence In Situ Hybridization (FISH) / A. Weise and T. Liehr -- Application of Multi-PRINS to Simultaneously Identify Chromosomes 18, X, and Y in Prenatal Diagnosis / M. Gadji [and others] -- Prenatal Diagnosis Using Array CGH / C.D. Kashork, A. Theisen and L.G. Shaffer -- Prenatal Detection of Chromosome Aneuploidy by Quantitative Fluorescence PCR / K. Mann, E. Petek and B. Pertl -- Real-time quantitative PCR for the detection of fetal aneuploidies / B.G. Zimmermann and L. Dudarewicz -- MLPA for Prenatal Diagnosis of Commonly Occurring Aneuploidies / J. Schouten and R.J. Galjaard -- MALDI-TOF Mass Spectrometry for Trisomy Detection / D.J. Huang, M.R. Nelson and W. Holzgreve -- Rapid Detection of Fetal Mendelian Disorders: Thalassemia and Sickle Cell Syndromes / J. Traeger-Synodinos, C. Vrettou and E. Kanavakis -- Rapid detection of fetal mendalian disorders: tay-sachs disease / E. Guetta and L. Peleg -- Arrayed primer extension reaction for genotyping on oligonucleotide microarray / J. Pullat and A. Metspalu -- A Fast Microelectronic Array for Screening and Prenatal Diagnosis of beta-Thalassemia / B. Foglieni [and others] -- RHD Genotyping from Maternal Plasma: Guidelines and Technical Challenges / N.D. Avent -- Isolation of Cell-Free DNA from Maternal Plasma Using Manual and Automated Systems / D.J. Huang [and others] -- Fetal DNA: Strategies for Optimal Recovery / T.J. Legler [and others] -- Quantification of circulatory fetal DNA in the plasma of pregnant women / B.G. Zimmermann, D.G. Maddocks and N.D. Avent -- Detection and Quantification of Fetal DNA in Maternal Plasma by Using LightCycler Technology / Y. Purwosunu, A. Sekizawa and T. Okai -- Size Fractionation of Cell-Free DNA in Maternal Plasma and Its Application in Noninvasive Detection of Fetal Single Gene Point Mutations / Y. Li, W. Holzgreve and S. Hahn -- Maldi-tof mass spectrometry for analyzing cell-free fetal DNA in maternal plasma / C. Ding -- Isolation of Cell-Free RNA from Maternal Plasma / X.Y. Zhong, W. Holzgreve and D.J. Huang -- A microarray approach for systematic identification of placental-derived RNA markers in maternal plasma / N.B. Tsui and Y.M. Lo -- A novel method to identify syncytiotrophoblast-derived RNA products representative of trisomy 21 placental RNA in maternal plasma / A.T. Go [and others] -- Method for extraction of high-quantity and -quality cell-free DNA from amniotic fluid / O. Lapaire, K.L. Johnson and D.W. Bianchi -- Detection of New Screening Markers for Fetal Aneuploidies in Maternal Plasma: A Proteomic Approach / C.S. Reddy, W. Holzgreve and S. Hahn |
Summary |
With molecular biology now allowing greater accuracy in prenatal diagnosis given amounts of fetal material as small as single cells, a major current focus has grown in the development of rapid, cost-effective diagnoses. In Prenatal Diagnosis, top experts provide cutting edge applications for the rapid assessment of fetal aneuploidies and Mendelian disorders on fetal material gained by invasive approaches, as well as procedures being validated for routine, non-invasive clinical analysis of cell free fetal DNA. Following the Methods in Molecular Biology series format, the chapters feature step-by-step laboratory protocols, lists of the necessary materials, and tips on troubleshooting and avoiding known pitfalls. Thorough and state-of-the-art, Prenatal Diagnosis is an ideal volume for researchers and molecular biologists invested in ever-growing field of prenatal medicine |
Notes |
"E-ISSn 1940-6029"--Title page verso |
Bibliography |
Includes bibliographical references and index |
Notes |
English |
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Print version record |
Subject |
Prenatal diagnosis.
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Fetus -- Diseases -- Molecular diagnosis
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Prenatal Diagnosis -- methods
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Fetal Diseases -- diagnosis
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Prenatal Diagnosis -- trends
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Prenatal Diagnosis
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Fetus -- Diseases -- Molecular diagnosis.
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Prenatal Diagnosis -- methods.
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Fetal Diseases -- diagnosis.
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Prenatal Diagnosis -- trends.
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Prenatal diagnosis.
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Prenatal diagnosis
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Genre/Form |
Laboratory manuals.
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Manuels de laboratoire.
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Form |
Electronic book
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Author |
Hahn, Sinuhe
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Jackson, Laird G
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ISBN |
9781588298034 |
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1588298035 |
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9781597450669 |
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1597450669 |
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