Pt. I. Themes. 1. Uncertainty and responsibility / Christopher Dowrick. 2. Evidence-based medicine and general practice / Lucy Frith. 3. Ethico-legal dilemmas within general practice: moral indeterminacy and abstract morality / Len Doyal. 4. The general practitioner and confidentiality / Jean McHale. 5. Patient-centredness: a history / Carl May and Nicola Mead. 6. Ethics and postmodernity / Sam Smith -- Pt. II. Topics. 7. The ethics of prescribing / Colin Bradley. 8. Depression in general practice / Roger Higgs. 9. Advance directives / Angus Dawson. 10. The ethics of research in general practice / Roger Jones