| Description |
1 online resource (xviii, 201 pages) : illustrations, portraits |
| Series |
Advances in experimental medicine and biology ; v. 594 |
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Advances in experimental medicine and biology ; v. 594.
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| Contents |
Protein misassembly: macromolecular crowding and molecular chaperones / R. John Ellis -- The cellular "networking" of mammalian HSP27 and its functions in the control of protein folding, redox state and apoptosis / André-Patrick Arrigo -- Molecular interaction network of the HSP90 chaperone system / Rongmin Zhao and Walid A. Houry -- Organization of the functions and components of the endoplasmic reticulum / Yuichiro Shimizu and Linda M. Hendershot -- Molecular crime and cellular punishment: active detoxification of misfolded and aggregated proteins in the cell by the chaperone and protease networks / Marie-Pierre Hinault and Pierre Goloubinoff -- Chaperones as parts of cellular networks / Peter Csermely, Csaba Söti and Gregory L. Blatch -- Chaperones as parts of organelle networks / György Szabadkai and Rosario Rizzuto -- Heat shock factor 1 as a coordinator of stress and developmental pathways / Julius Anckar and Lea Sistonen -- Chaperone regulation of the heat shock protein response / Richard Voellmy and Frank Boellmann -- Mechanisms of activation and regulation of the heat shock-sensitive signaling pathways / Sébastien Ian Nadeau and Jacques Landry -- Membrane-regulated stress response: a theoretical and practical approach / László Vígh [and others] -- Beyond the lipid hypothesis: mechanisms underlying phenotypic plasticity in inducible cold tolerance / Scott A.L. Hayward [and others] -- Trehalose as a "chemical chaperone:" fact and fantasy / John H. Crowe -- Chaperones as part of immune networks / Zoltán Prohászka -- The stress of misfolded proteins: C. elegans models for neurodegenerative disease and aging / Heather R. Brignull, James F. Morley and Richard I. Morimoto -- HSP90 and developmental networks / Suzannah Rutherford, Jennifer R. Knapp and Peter Csermely |
| Summary |
This book is authored by an exciting mixture of top experts and young rising stars from the fields of molecular chaperones and stress adaptation. In addition to giving a comprehensive summary with original references to their field, all authors share their hypotheses and vision on future trends with the reader. The book makes a novel synthesis of the molecular aspects of the stress response and long term adaptation processes with the system biology approach of biological networks. A novel perspective of "old facts" is provided in each chapter, where "old" means only 5-10 years in this rapidly expanding field. The integrative, holistic nature of the book makes it an excellent reading for undergraduates, graduate students and fellow scientists extending their knowledge and studies |
| Analysis |
biochemie |
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biochemistry |
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biofysica |
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biophysics |
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celbiologie |
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cellular biology |
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immunologie |
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immunology |
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levenswetenschappen |
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life sciences |
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biomedische wetenschappen |
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biomedicine |
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Biology (General) |
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Biologie (algemeen) |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| In |
Springer e-books |
| Subject |
Stress (Physiology)
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Molecular chaperones.
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Protein folding.
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Heat shock proteins.
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Biochemistry.
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Stress, Physiological -- physiopathology
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Molecular Chaperones
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Protein Folding
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Heat-Shock Proteins
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Biochemistry
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biochemistry.
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SCIENCE -- Life Sciences -- Biochemistry.
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Cell physiology.
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Molecular chaperones.
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Stress (Physiology)
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Protein folding.
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Heat shock proteins.
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Stress.
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Molécules chaperonnes.
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Protéines -- Repliement.
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Protéines de choc thermique.
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Moleculaire biologie.
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Stress -- physiopathology.
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Biomédecine.
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Sciences de la vie.
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Heat shock proteins
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Molecular chaperones
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Protein folding
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Stress (Physiology)
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Stress.
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Moleculaire biologie.
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| Form |
Electronic book
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| Author |
Csermely, Peter.
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Vígh, László, prof.
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| LC no. |
2007295588 |
| ISBN |
9780387399751 |
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0387399755 |
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9780387399744 |
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0387399747 |
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1280970057 |
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9781280970054 |
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