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Title Aggregation of therapeutic proteins / edited by Wei Wang, Christopher J. Roberts
Published Hoboken, N.J. : Wiley, ©2010


Description 1 online resource (xxii, 486 pages) : illustrations (some color)
Contents AGGREGATION OF THERAPEUTIC PROTEINS; CONTENTS; PREFACE; CONTRIBUTORS; CHAPTER 1: Fundamental Structures and Behaviors of Proteins; CHAPTER 2: Protein Aggregation Pathways, Kinetics, and Thermodynamics; CHAPTER 3: Identification and Impact of Aggregation-Prone Regions in Proteins and Therapeutic Monoclonal Antibodies; CHAPTER 4: External Factors Affecting Protein Aggregation; CHAPTER 5: Experimental Detection and Characterization of Protein Aggregates; CHAPTER 6: Approaches to Control Protein Aggregation during Bulk Production
Summary "While significant progress has been made in the past decade, the current understanding of protein aggregation and its consequences is still immature. Aggregation of Therapeutic Proteins provides an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. This book also covers an overview on the causes, consequences, characterization, and control of the aggregation of therapeutic proteins. The knowledge in this book will help pharmaceutical scientists in the development of therapeutic proteins, and also instigate further scientific investigations in this area"--Provided by publisher
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Protein drugs.
Aggregation (Chemistry)
Cell aggregation.
Proteins -- Conformation.
Recombinant Proteins -- therapeutic use
Cell Aggregation
Protein Conformation
Protein Folding
Recombinant Proteins -- metabolism
MEDICAL -- Chemotherapy.
Proteins -- Conformation
Cell aggregation
Aggregation (Chemistry)
Protein drugs
Form Electronic book
Author Wang, Wei, 1957 March 10-
Roberts, Christopher John, 1972-
LC no. 2010008428
ISBN 9780470769812