FOLDASES CATALYZING THE FORMATION AND ISOMERIZATION OF DISULFIDE BONDS IN PROTEINS -- Contents -- Preface -- Introduction -- Eukaryotic Protein Disulfide Isomerase (PDI) -- 1.1. The Role of Protein Disulfide Isomerase in the Endoplasmic Reticulum -- 1.2. Modular Organization of the PDI Molecule and the Role of Different Domains -- 1.3. Functional Properties of PDI Active Centers. The pKa Values of Essential Cysteine Residues -- 1.4. Disulfide Isomerization: The Essential Function of PDI -- 1.5. Dithiol Oxidation Catalyzed by PDI
1.6. The Role of Glutathione in Oxidative Protein Folding in Endoplasmic Reticulum Disulfide Bond Formation and Isomerization in Prokaryotes -- 2.1. A Pathway for Disulfide Bond Formation in the Periplasm -- 2.2. Similarities in Prokaryotic and Eukaryotic Disulfide Bond-Forming Pathways -- 2.3. A Pathway for Disulfide Bond Isomerization in the Periplasm -- Conclusion -- References -- Index
Bibliography
Includes bibliographical references (pages 61-68) and index