| Description |
1 online resource |
| Contents |
Cover13; -- Protein Hydrolysates in Biotechnology -- Preface -- Acknowledgements -- Contents -- Contributors -- Chapter 1: Applications of Protein Hydrolysates in Biotechnology -- Introduction -- What Are Protein Hydrolysates? -- Evolution of Protein Hydrolysates -- Applications of Protein Hydrolysates in the Biotechnology Industry -- Future Directions -- References -- Chapter 2: State of the Art Manufacturing of Protein Hydrolysates -- Introduction -- Current Practices of Different Manufacturing Methods of Protein Hydrolysates -- Generic Flow of Manufacturing Process of Protein Hydrolysates -- Controlling Inconsistencies of Protein Hydrolysates During Manufacturing -- Selection of Raw Materials -- End Use of Protein Hydrolysates Dictates the Downstream Processing -- Plate and Frame Filtration -- Different Methods of Concentration and Drying -- Considerations for Plant Design and Layout -- Concerns of the Biotechnology Industry for Regulatory Support from Protein Hydrolysate Manufacturers -- Specifications and Sampling -- Future Trends -- Continuous Process -- Innovative Technologies -- Collaboration and Partnerships -- References -- Chapter 3: Towards an Understanding of How Protein Hydrolysates Stimulate More Efficient Biosynthesis in Cultured Cells -- Introduction -- History of Cell Culture Media -- Animal Cell Culture Developments -- Serum- and Animal-Free Medium Adaptations -- Cellular Metabolism, Tumor Cells in Culture, and the Influence of Protein Hydrolysates -- Enhanced Production by Cultured Cells on Plant-Derived Protein Hydrolysates -- Development of Plant-Derived Protein Hydrolysates for Cell Culture Media -- Discussion -- Summary and Outlook -- References -- Chapter 4: Benefits and Limitations of Protein Hydrolysates as Components of Serum-Free Media for Animal Cell Culture Applicati -- Introduction -- Results -- Insect Cell Culture -- Virus Production in Mammalian Cells -- Recombinant Protein Production by CHO Cells -- Cationic Lipid Transfection -- Discussion -- Advantages -- Disadvantages -- Future Developments -- Processing Improvements -- Hydrolysate Characterization -- Product Development -- Chemically-Defined Medium -- References -- Chapter 5: Oligopeptides as External Molecular Signals Affecting Growth and Death in Animal Cell Cultures -- Introduction -- Results and Discussion -- Basic Features of the Action of Synthetic Oligopeptides -- Suppression of Programmed Cell Death -- Feeding the Peptide-Supplemented Cultures -- Intact Peptide Cannot Be Replaced by Amino Acids Constituting the Peptide -- Integrity of the Peptides in the Culture -- Shift in the Cell-Cycle Phases Distribution -- Summary and Conclusions -- Future Developments -- References -- Chapter 6: Use of Protein Hydrolysates in Industrial Starter Culture Fermentations -- Introduction -- Industrial Applications of Starter Cultures -- Production of Starter Cultures -- Design of Fermentation Media -- Energy and Carbon Sources -- Nitrogen Requirements and Uptake Systems in LAB -- Protein Hydrolysates: A Source of Nitrogen and Growth Factors -- Criteria for Selection of Protein Hydrolysates -- Nutritional Requirements and Use of Protein Hydrolysates During Fermentations -- Genus Lactococcus -- Genus Lactobacillus -- Genus Streptococcus -- Genus Bifidobacterium -- Genus Pediococcus |
| Summary |
The protein hydrolysates industry is growing rapidly yet there is no single book that describes the challenges and opportunities for manufacturers and end users, techniques used in manufacturing, characterization and screening of protein hydrolysates, their applications in a wide variety of industries in biotechnology. One of the misconceptions in using protein hydrolysates in fermentations is that the end user believes and uses it as a mere nitrogen source. However, the functionality of the product obtained is not necessarily due to protein hydrolysates alone because it may not be a pure peptide or a combination of peptides and may contain carbohydrates, lipids, micronutrients, etc., present in the raw material used or sometimes the manufacturers deliberately add to the process to bring unique functionality. Only a handful of manufacturers dictate this market that tend to keep manufacturing process proprietary making it harder to understand. This book will close the gap by unfolding information on latest developments |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| In |
Springer eBooks |
| Subject |
Protein hydrolysates.
|
|
Biotechnology.
|
|
Bioengineering.
|
|
bioengineering.
|
|
SCIENCE -- Biotechnology.
|
|
Protein hydrolysates.
|
|
Biotechnology.
|
|
Chimie.
|
|
Science des matériaux.
|
|
Bioengineering
|
|
Biotechnology
|
|
Protein hydrolysates
|
| Form |
Electronic book
|
| Author |
Pasupuleti, Vijai K.
|
|
Demain, A. L. (Arnold L.), 1927-
|
| ISBN |
9781402066740 |
|
1402066740 |
|
1282980688 |
|
9781282980686 |
|
