Title Serpins and protein kinase inhibitors : novel functions, structural features and molecular mechanisms / Bojidor Georgiev and Sava Markovski, editors

Published New York : Nova Science Publishers, ©2010

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Description 1 online resource (xiii, 257 pages) : illustrations (some color) Series Protein biochemistry, synthesis, structure, and cellular functions series Protein biochemistry, synthesis, structure, and cellular functions series. Contents Serpin-related diseases / Aleksandra Topic -- The roles of mammalian mitogen-activated protein kinase-activating protein kinases (MAPKAPKs) in cell cycle control / Sergiy Kostenko [and others] -- Rho-kinase inhibitor in kidney disease / Toshio Nishikimi -- Targeting the epidermal growth factor receptor pathway in glioblastoma multiforme and other intracranial malignancies / Marc-Eric Halatsch, Georg Karpel-Massler -- The serine proteinase inhibitor Z alpha-1 antitrypsin : acting on the NF-kappaB system for cytotoxicity / Matthew William Lawless -- Src family kinase inhibitors in cancer therapy / Faye M. Johnson, Gary E. Gallick -- Protein kinase inhibitors in cancer / Yiguo Hu, Shaoguang Li -- Protein kinase inhibitors in the treatment of malignant liver and kidney tumors / Panagiotis Samaras, Frank Stenner -- PAI-1 and the diet-induced obesity phenotype : background effects and inbreeding / Bart M. De Taeye, Tatiana Novitskaya, and Douglas E. Vaughan -- The structure of 1-proteinase inhibitor polymer : facts and hypothesis / Ewa Marszal -- SERPINA5 expression in the male reproductive tract is altered with advanced age / Matthew D. Anway -- Vaspin : visceral adipose tissue-derived serpin with insulin-sensitizing effects / Jun Wada -- Effect of alpha2-antiplasmin on tissue remodeling / Yosuke Kanno and Hiroyuki Matsuno Bibliography Includes bibliographical references and index Notes Print version record Subject Serine proteinases -- Inhibitors. Serpins -- Physiological effect Protein kinases -- Physiological effect Serpins -- physiology Protein Kinase Inhibitors Serine Proteinase Inhibitors -- physiology Serine Proteinase Inhibitors SCIENCE -- Life Sciences -- Biochemistry. Protein kinases -- Physiological effect Serine proteinases -- Inhibitors Serpins -- Physiological effect Form Electronic book Author Georgiev, Bojidor Markovski, Sava ISBN 9781612093505 1612093507

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