| Description |
1 online resource |
| Series |
Drug discovery series ; 8 |
|
Drug discovery series ; 8
|
| Contents |
High-throughput gene cloning using the gateway\256 technology / Scott N. Peterson [and others] -- Protein expression for microarrays / Harry H. Yim, Thomas G. Chappell, and Steven H. Harwood -- Emerging trend: cell-free protein expression / Federico Katzen and Wieslaw Kudlicki -- The critical role of surface chemistry in protein microarrays / Athena Guo and X.-Y. Zhu -- Fabrication of sol-gel-derived protein microarrays for diagnostics and screening / Nicholas Rupcich and John D. Brennan -- Printing and QC of functional protein microarrays / Dee Shen, Fang X. Zhou, and Barry Schweitzer -- Protein engineering for surface attachment / Aparna Girish, Grace Y.J. Chen, and Shao Q. Yao -- Protein in situ arrays through cell-free protein synthesis / Mingyue He [and others] -- Fluorescent detection methods for protein microarrays / Steven Roman and Scott Clarke -- Functional analysis of protein interactions using surface plasmon resonance-based microarrays / Alan McWhirter and Stefan L. -- Leaving the surface behind: at the intersection of protein microarrays and mass spectrometry / Darrell P. Chandler [and others] -- High-resolution label-free detection applied to protein microarray research / Lance G. Laing and Brian Cunningham -- Studying protein\u2013 protein interactions with protein microarrays: rapid identification of 14-3-3 protein binding partners / Jun-ichi Satoh -- A combined force of chemical genetics and protein microarrays / Heng Zhu and Jing Huang -- Antibody profiling for protein drug development and clinical development / Steve H. Herrmann -- Humoral response profiling using protein microarrays / Arun Sreekumar [and others] -- DNA interactions with arrayed proteins / Marina Snapyan and Vehary Sakanyan -- G protein\u2013 coupled receptor microarrays for drug discovery / John Salon [and others] -- Kinase substrate identification using yeast protein microarrays / Geeta Devgan and Michael Snyder -- Protein microarray image analysis / Minzi Ruan -- The analysis of protein arrays / Brad Love -- Evaluating precision and recall in functional protein arrays / Keith Robison -- Visualization of protein microarray data / Kevin Clancy |
| Summary |
An ideal text for biotechnologists, protein chemists, and biochemists, Functional Protein Microarrays in Drug Discovery explores all aspects of functional protein microarrays, including basic principles, methods, and applications. The book discusses the generation of functional protein content and describes both standard and state-of-the-art fabrication methods. It reviews current and next generation approaches to assay detection and presents a wide range of applications, from biomolecular interaction discovery and characterization to immune response profiling. The book also addresses several |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Protein microarrays.
|
|
Drugs -- Design.
|
|
Proteins -- analysis
|
|
Drug Design
|
|
Protein Array Analysis
|
|
SCIENCE -- Life Sciences -- Biochemistry.
|
|
Drugs -- Design
|
|
Protein microarrays
|
| Form |
Electronic book
|
| Author |
Predki, Paul F., 1964-
|
| ISBN |
9781420009842 |
|
1420009842 |
|
1281081140 |
|
9781281081148 |
|
