| Description |
1 online resource (xiv, 445 pages) : illustrations |
| Series |
Neuromethods, 0893-2336 ; 30 |
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Neuromethods ; 30.
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| Contents |
Analysis of Protein Phosphorylation in Intact Cells and Extracts / S. Ivar Walaas and Anne Carine Ostvold -- Analysis of Protein Dephosphorylation in Intact Cells and Extracts / Shelley Halpain -- Protein Phosphorylation and Dephosphorylation in Isolated Nerve Terminals (Synaptosomes) / Talvinder S. Sirha -- Protein Kinase and Phosphotase Inhibitors: Applications in Neuroscience / Hugh C. Hemmings, Jr. -- Phosphorylation State-Specific Antibodies / Andres J. Czernik, Jeffrey Mathers and Sheenah M. Mische -- Protein Tyrosine Phosphorylation / Pascal Derkinderen and Jean-Antoine Girault -- Identification of Posttranslational Modification Sites by Site-Directed Mutagenesis / James A. Bibb and Edgar F. da Cruz e Silva -- Protein Methylation in the Nervous System / Darin J. Weber and Philip N. McFadden -- Long-Chain Fatty Acylation of Proteins / Sean I. Patterson and J.H. Pate Skene -- Protein ADP-Ribosylation / Keith D. Philibert and Henk Zwiers |
| Summary |
Hugh Hemmings' Regulatory Protein Modification: Techniques and Protocols offers critical reviews of major topics concerning posttranslational protein modification in neurons, as well as a comprehensive collection of state-of-the-art techniques for their analysis. Its distinguished international contributors provide detailed and specific methods for studying protein phosphorylation/dephospohorylation, methylation, long chain fatty acylation, ADP-ribosylation, glycosylation, and glycosylphosphatidylinositol anchors. Using both conventional analytical and novel molecular biological approaches, these experts discuss the techniques and reagents and cite numerous examples from the neuroscience literature in a way that allows investigators to determine the best experimental approaches for their own systems. They also offer a complete review of protein kinase and phosphatase inhibitors techniques and their applications today. Regulatory Protein Modification: Techniques and Protocols will prove an exceptionally valuable resource for both experienced and new investigators working in neuronal and nonneuronal systems |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL |
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Print version record |
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digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL |
| Subject |
Proteins -- Chemical modification -- Handbooks, manuals, etc
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Proteins -- Analysis -- Handbooks, manuals, etc
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Neurosciences -- Handbooks, manuals, etc
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Protein kinases -- Handbooks, manuals, etc
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Phosphorylation.
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Protein kinases.
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Phosphorylation
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Protein Processing, Post-Translational -- physiology
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Neurons -- physiology
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Protein Engineering -- methods
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Protein Kinases
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Synaptosomes -- chemistry
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Phosphorylation
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Neurosciences
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Protein kinases
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Proteins -- Analysis
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Proteins -- Chemical modification
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Nervenzelle
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Proteine
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Posttranslationale Änderung
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Aufsatzsammlung
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| Genre/Form |
manuals (instructional materials)
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handbooks.
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Laboratory manuals
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Handbooks and manuals
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Handbooks and manuals.
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Laboratory manuals.
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Manuels de laboratoire.
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Guides et manuels.
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| Form |
Electronic book
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| Author |
Hemmings, Hugh C., Jr
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| ISBN |
9781592596355 |
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1592596355 |
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