Proteomics technologies -- Cell signaling proteomics -- Tumor proteomics -- Bioinformatics and regulatory aspects of proteomics
Summary
"Over the past 20 years, there have been tremendous advances in our understanding of how normal cells transform to cancer and the importance of signaling pathways in cancer initiation and progression. To keep pace, proteomics technologies must constantly be improved. In Cancer Proteomics, the authors collectively outline the current status of proteomics in cancer therapy and describe the existing technologies used in proteomics that allow for protein profiling and the identification of druggable targets in human samples. Mass spectrometry-based protein characterization and protein microarrays hold great promise for predicting response to specific drugs in cancer therapy. This book offers a broad perspective on topics related to the use of proteomic strategies in cancer therapy and addresses challenges that may arise from its application in daily practice."--Jacket
