| Description |
1 online resource (384 pages) |
| Contents |
Purine and Pyrimidine Metabolism; Contents; Chairman's opening remarks; Purine and pyrimidine metabolism : pathways, pitfalls and perturbations; Discussion; Microbial models and regulatory elements in the control of purine metabolism; Discussion; Molecular nature of enzyme regulation in purine biosynthesis; Discussion; Genetic heterogeneity at the locus for hypoxanthine-guanine phosphoribosyltransferase; Discussion; Factors in the pathogenesis of the brain damage and anaemia in the Lesch-Nyhan syndrome; Discussion |
|
Hypoxanthine-guanine phosphoribosyltransferase activity in individual erythrocytes: autoradiographic studies in heterozygotDiscussion; Purine biosynthesis in mutant mammalian cells; Discussion; Purine and pyrimidine nucleotides in some mutant human lymphoblasts; Discussion; Superactivity of phosphoribosylpyrophosphate synthetase, due to feedback resistance, causing purine overproduction and gout; Discussion; Dietary feedback regulation of purine and pyrimidine biosynthesis in man; Discussion; Implications of disorders of purine metabolism for the kidney and the urinary tract; Discussion |
|
The role of de novo purine synthesis in lymphocyte transformationDiscussion; Purine metabolism and control of cell proliferation; Discussion; The effect of adenosine on lymphoid cell proliferation and antibody formation; Discussion; Characterization of human adenosine deaminase; Discussion; The purinergic nerve hypothesis; Discussion; Inherited metabolic disease: prospects for the future in both basic and clinical research; Discussion; General discussion; Purine as regulators; Extracellular effects of adenosine; Membrane transport; Pyrimidine metabolism and immune function |
|
Allopurinol and purine transportModel systems for the study of purine and pyrimidine metabolism and their limitations; Animal models; Assessment of treatment : the Lesch-Nyhan syndrome; Ribose 5-phosphate and the oxidative pentose shunt in the regulation of purine synthesis de novo; Index of contributors; Subject index |
| Subject |
Purines -- Metabolism -- Congresses
|
|
Pyrimidines -- Metabolism -- Congresses
|
|
Purines -- Metabolism
|
|
Pyrimidines -- Metabolism
|
| Genre/Form |
Conference papers and proceedings
|
| Form |
Electronic book
|
| ISBN |
1280783672 |
|
9781280783678 |
|
9780470717981 |
|
047071798X |
|
