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E-book

Title Quantitative trait loci (QTL) : methods and protocols / edited by Scott A. Rifkin
Published New York : Humana Press, ©2012

Copies

Description 1 online resource (xi, 331 pages) : illustrations (some color)
Series Methods in molecular biology ; v. 871
Methods in molecular biology (Clifton, N.J.) ; v. 871
Contents Backcross populations and near isogenic lines / Rik Kooke, Erik Wijnker, and Joost J.B. Keurentjes -- F₂ designs for QTL analysis / Yuan-Ming Zhang -- Design and construction of recombinant inbred lines / Daniel A. Pollard -- Two flavors of bulk segregant analysis in yeast / Maitreya J. Dunham -- Selecting markers and evaluating coverage / Matthew A. Cleveland and Nader Deeb -- Composite interval mapping and multiple interval mapping : procedures and guidelines for using windows QTL cartographer / Luciano Da Costa E. Silva, Shengchu Wang, and Zhao-Bang Zeng -- Design database for quantitative trait loci (QTL) data warehouse, data mining, and meta-analysis / Zhi-Liang Hu, James M. Reecy, and Xiao-Lin Wu -- Meta-analysis of QTL mapping experiments / Xiao-Lin Wu and Zhi-Liang Hu -- Using eQTLs to reconstruct gene regulatory networks / Lin S. Chen -- Estimation and interpretation of genetic effects with epistasis using the NOIA model / Jose M. Alvarez-Castro, Orjan Carlborg, and Lars Ronnegard -- Identifying QTL for multiple complex traits in experimental crosses / Samprit Banerjee and Nengjun Yi -- Functional mapping of developmental processes : theory, applications, and prospects / Kiranmoy Das [and others] -- Statistical models for genetic mapping in polyploids : challenges and opportunities / Jiahan Li [and others] -- eQTL / Lun Li, Xianghua Zhang, and Hongyu Zhao -- Genetic mapping of quantitative trait loci for disease -- related phenotypes / Marcella Devoto and Mario Falchi -- Quantitative trait locus analysis in haplodiploid hymenoptera / Jurgen Gadau, Christof Pietsch, and Leo W. Beukeboom
Summary Over the last two decades advances in genotyping technology, and the development of quantitative genetic analytical techniques have made it possible to dissect complex traits and link quantitative variation in traits to allelic variation on chromosomes or quantitative trait loci (QTLs). In Quantitative Trait Loci (QTLs):Methods and Protocols, expert researchers in the field detail methods and techniques that focus on specific components of the entire process of quantitative train loci experiments. These include methods and techniques for the mapping populations, identifying quantitative trait loci, extending the power of quantitative trait locus analysis, and case studies. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Quantitative Trait Loci (QTLs):Methods and Protocols aids scientists in the further study of the links between phenotypic and genotypic variation in fields from medicine to agriculture, from molecular biology to evolution to ecology
Analysis biomedische wetenschappen
biomedicine
humane genetica
human genetics
loci voor kwantitatief kenmerk
quantitative trait loci
methodologie
methodology
protocollen
protocols
Medicine (General)
Genetics (General)
Geneeskunde (algemeen)
Genetica (algemeen)
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Genetics -- Statistical methods
Gene mapping.
Phenotype.
Quantitative Trait Loci
Chromosome Mapping -- methods
Chromosome Mapping
Phenotype
Gene mapping
Genetics -- Statistical methods
Phenotype
Genre/Form Laboratory manuals.
Manuels de laboratoire.
Form Electronic book
Author Rifkin, Scott A.
ISBN 9781617797859
1617797855