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RNA-dependent DNA polymerase -- See Reverse transcriptase


  1
 

RNA-directed DNA polymerase -- See Reverse transcriptase


  1
RNA-Directed DNA Polymerase   3
RNA, Double-Stranded   2
RNA, Double-Stranded -- metabolism : Adenosine deaminases acting on RNA (ADARs) and a-to-i editing / Charles E. Samuel, editor  2012 1
RNA -- drug effects : The many faces of RNA / edited by D.S. Eggleston, C.D. Prescott, and N.D. Pearson  1998 1
RNA Editing   11
RNA editing -- Handbooks, manuals, etc.   2
 

RNA Editings -- See RNA Editing


A process that changes the nucleotide sequence of mRNA from that of the DNA template encoding it. Some major classes of RNA editing are as follows: 1, the conversion of cytosine to uracil in mRNA; 2, the addition of variable number of guanines at pre-determined sites; and 3, the addition and deletion of uracils, templated by guide-RNAs (RNA, GUIDE)
  1
 

RNA enzymes -- See Catalytic RNA


  1
RNA -- Evolution.   2
 

RNA Folding -- See Also Nucleic Acid Conformation


The spatial arrangement of the atoms of a nucleic acid or polynucleotide that results in its characteristic 3-dimensional shape
  1
RNA Folding   2
 

RNA Foldings -- See RNA Folding


The processes of RNA tertiary structure formation
  1
 

RNA, G-Quadruplexes -- See G-Quadruplexes


Higher-order DNA and RNA structures formed from guanine-rich sequences. They are formed around a core of at least 2 stacked tetrads of hydrogen-bonded GUANINE bases. They can be formed from one two or four separate strands of DNA (or RNA) and can display a wide variety of topologies, which are a consequence of various combinations of strand direction, length, and sequence. (From Nucleic Acids Res. 2006;34(19):5402-15)
  1
 

RNA Gene Products -- See RNA


A polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached. RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
  1
RNA -- genetics. : Genes VIII / Benjamin Lewin  2004 1
 

RNA Glycosylase -- See Ribosome Inactivating Proteins


N-Glycosidases that remove adenines from RIBOSOMAL RNA, depurinating the conserved alpha-sarcin loop of 28S RIBOSOMAL RNA. They often consist of a toxic A subunit and a binding lectin B subunit. They may be considered as PROTEIN SYNTHESIS INHIBITORS. They are found in many PLANTS and have cytotoxic and antiviral activity
  1
 

RNA, Guide -- See Also RNA Editing


A process that changes the nucleotide sequence of mRNA from that of the DNA template encoding it. Some major classes of RNA editing are as follows: 1, the conversion of cytosine to uracil in mRNA; 2, the addition of variable number of guanines at pre-determined sites; and 3, the addition and deletion of uracils, templated by guide-RNAs (RNA, GUIDE)
  1
RNA -- Handbooks, manuals, etc.   2
RNA -- Health aspects   2
RNA Helicases : RNA helicases / editor, Eckhard Jankowsky  2010 1
RNA -- immunology : Nucleic acids in innate immunity / edited by Ken J. Ishii, Shizuo Akira  2008 1
  RNA-Induced Silencing Complex -- 2 Related Subjects   2
 

RNA Instability -- See RNA Stability


The extent to which an RNA molecule retains its structural integrity and resists degradation by RNASE, and base-catalyzed HYDROLYSIS, under changing in vivo or in vitro conditions
  1
  RNA Interference -- 2 Related Subjects   2
RNA interference.   17
RNA Interference -- physiology : RNA Interference from Biology to Therapeutics / Kenneth A. Howard  2013 1
RNA -- isolation & purification   3
RNA -- Laboratory manuals : Gene silencing by RNA interference : technology and application / edited by Muhammad Sohail  2005 1
RNA-ligand interactions : Exploring Protein Structure : Principles and Practice / by Tim Skern  2018 1
 

RNA, Long Non-Coding -- See RNA, Long Noncoding


A class of untranslated RNA molecules that are typically greater than 200 nucleotides in length and do not code for proteins. Members of this class have been found to play roles in transcriptional regulation, post-transcriptional processing, CHROMATIN REMODELING, and in the epigenetic control of chromatin
  1
 

RNA, Long Non-Protein-Coding -- See RNA, Long Noncoding


A class of untranslated RNA molecules that are typically greater than 200 nucleotides in length and do not code for proteins. Members of this class have been found to play roles in transcriptional regulation, post-transcriptional processing, CHROMATIN REMODELING, and in the epigenetic control of chromatin
  1
 

RNA, Long Non-Translated -- See RNA, Long Noncoding


A class of untranslated RNA molecules that are typically greater than 200 nucleotides in length and do not code for proteins. Members of this class have been found to play roles in transcriptional regulation, post-transcriptional processing, CHROMATIN REMODELING, and in the epigenetic control of chromatin
  1
RNA, Long Noncoding : Long non-coding RNA : the dark side of the genome / Antonin Morillon ; RNA set coordinated by Marie-Christine Maurel  2018 1
RNA, Long Noncoding -- chemistry : The chemical biology of long noncoding RNAs / Stefan Jurga, Jan Barciszewski, editors  2020 1
 

RNA, Long Untranslated -- See RNA, Long Noncoding


A class of untranslated RNA molecules that are typically greater than 200 nucleotides in length and do not code for proteins. Members of this class have been found to play roles in transcriptional regulation, post-transcriptional processing, CHROMATIN REMODELING, and in the epigenetic control of chromatin
  1
 

RNA Manipulation, Immune -- See Immunotherapy, Active


Active immunization where vaccine is administered for therapeutic or preventive purposes. This can include administration of immunopotentiating agents such as BCG vaccine and Corynebacterium parvum as well as biological response modifiers such as interferons, interleukins, and colony-stimulating factors in order to directly stimulate the immune system
  1
 

RNA Manipulations, Immune -- See Immunotherapy, Active


Active immunization where vaccine is administered for therapeutic or preventive purposes. This can include administration of immunopotentiating agents such as BCG vaccine and Corynebacterium parvum as well as biological response modifiers such as interferons, interleukins, and colony-stimulating factors in order to directly stimulate the immune system
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RNA, Messenger   3
RNA, Messenger -- analysis.   2
 

RNA, Messenger, Editing -- See RNA Editing


A process that changes the nucleotide sequence of mRNA from that of the DNA template encoding it. Some major classes of RNA editing are as follows: 1, the conversion of cytosine to uracil in mRNA; 2, the addition of variable number of guanines at pre-determined sites; and 3, the addition and deletion of uracils, templated by guide-RNAs (RNA, GUIDE)
  1
RNA, Messenger -- genetics   3
 

RNA, Messenger, Polyadenylated -- See RNA, Messenger


RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm
  1
 

RNA, Messenger, Precursors -- See RNA Precursors


RNA transcripts of the DNA that are in some unfinished stage of post-transcriptional processing (RNA PROCESSING, POST-TRANSCRIPTIONAL) required for function. RNA precursors may undergo several steps of RNA SPLICING during which the phosphodiester bonds at exon-intron boundaries are cleaved and the introns are excised. Consequently a new bond is formed between the ends of the exons. Resulting mature RNAs can then be used; for example, mature mRNA (RNA, MESSENGER) is used as a template for protein production
  1
 

RNA, Messenger, Splicing -- See RNA Splicing


The ultimate exclusion of nonsense sequences or intervening sequences (introns) before the final RNA transcript is sent to the cytoplasm
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RNA -- metabolism   5
RNA -- Metabolism -- Regulation : Post-transcriptional regulation by STAR proteins : control of RNA metabolism in development and disease / edited by Talila Volk, Karen Artzt  2010 1
RNA -- Methodology. : RNA processing. Part A, General methods / edited by James E. Dahlberg, John N. Abelson  1989 1
 

RNA, Micro -- See MicroRNAs


Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing
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