| Description |
1 online resource (vii, 464 pages) : illustrations |
| Contents |
Structures of microRNA precursors / P. Kozlowski [and others] -- Small RNA technologies: siRNA, miRNA, antagomiR, target mimicry, miRNA sponge and miRNA profiling / G. Tang [and others] -- RNA interference expression vectors based on miRNAs and RNA splicing / A.N. Bonsra, J. Yonekubo and G. Du -- Recent application of intronic microRNA agents in cosmetics / S.-L. Lin, D.T.S. Wu and S.-Y. Ying -- MicroRNA profiling in CNS tissue using microarrays / R. Saba and S.A. Booth -- MicroRNA and erythroid differentiation / M. Zhan and C.-Z. Song -- Homeotic miRNAs: From development to pathologies / M. Ameyar-Zazoua [and others] -- MicroRNA in muscle development and function / Z. Deng and D.-Z. Wang -- MicroRNAs and regenerative medicine / J. Wu and Z. Yang -- Role of mir-302 microRNA family in stem cell pluripotency and renewal / S.-L. Lin and S.-Y. Ying -- Epigenetic regulation of miRNA in stem cells / K. Szulwach [and others] -- Identification of cellular targets for virally-encoded miRNAs by ectopic expression and gene expression profiling / M.A. Samols, R.L. Skalsky and R. Renne -- MicroRNA in neuropsychiatric diseases / E.I. Rogaev, D.V. Islamgulov and A.P. Grigorenko -- Role of repeat-associated MicroRNA (ramRNA) in fragile X syndrome (FXS) / S.-L. Lin and S.-Y. Ying -- miRNA and schizophrenia / D.O. Perkins and C.D. Jeffries -- SNPs in microRNA and microRNA target sites associated with human cancers / S.-H. Shen and Z. Yu -- Expression and function of microRNAs in chronic myeloid leukemia / M. Scherr, L. Venturini and M. Eder -- MicroRNAs in vascular neointimal lesion formation / C. Zhang -- MicroRNA in cutaneous wound healing / C.K. Sen and S. Roy -- CpG island hypermethylation, miRNAs, and human cancer / A. Lujambio and M. Esteller -- Microarray profiling of microRNA changes in cells that express HIV-1 proteins / M.L. Yeung and K.-T. Jeang -- microRNA-associated therapies / A. Saumet [and others] -- The use of RNAi to elucidate and manipulate secondary metabolite synthesis in plants / G.J. Wagner and A.B. Kroumova |
| Summary |
Nearly 97% of the human genome is the non-coding DNA, which varies from one species to another, and changes in these sequences are frequently noticed to manifest clinical and circumstantial malfunction. Numerous non-protein-coding genes are recently found to encode microRNAs, which are responsible for RNA-mediated gene silencing through RNA interference (RNAi)-like pathways. MicroRNAs (miRNAs), small single-stranded 17a "25 nucleotide RNAs capable of interfering with intracellular messenger RNAs (mRNAs) that contain either complete or partial complementarity, are useful for the design of |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Small interfering RNA.
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Gene silencing.
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Non-coding RNA.
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Small interfering RNA -- Therapeutic use
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RNA, Small Interfering
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RNA, Untranslated
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Biomédecine.
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Sciences de la vie.
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Gene silencing.
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Non-coding RNA.
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Small interfering RNA.
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| Form |
Electronic book
|
| Author |
Ying, Shao-Yao
|
| ISBN |
9781402085338 |
|
1402085338 |
|
9781402085321 |
|
140208532X |
|
