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Title Current perspectives in microRNAs (miRNA) / editor Shao Yao Ying
Published [London?] : Springer, ©2008


Description 1 online resource (vii, 464 pages) : illustrations
Contents Structures of microRNA precursors / P. Kozlowski [and others] -- Small RNA technologies: siRNA, miRNA, antagomiR, target mimicry, miRNA sponge and miRNA profiling / G. Tang [and others] -- RNA interference expression vectors based on miRNAs and RNA splicing / A.N. Bonsra, J. Yonekubo and G. Du -- Recent application of intronic microRNA agents in cosmetics / S.-L. Lin, D.T.S. Wu and S.-Y. Ying -- MicroRNA profiling in CNS tissue using microarrays / R. Saba and S.A. Booth -- MicroRNA and erythroid differentiation / M. Zhan and C.-Z. Song -- Homeotic miRNAs: From development to pathologies / M. Ameyar-Zazoua [and others] -- MicroRNA in muscle development and function / Z. Deng and D.-Z. Wang -- MicroRNAs and regenerative medicine / J. Wu and Z. Yang -- Role of mir-302 microRNA family in stem cell pluripotency and renewal / S.-L. Lin and S.-Y. Ying -- Epigenetic regulation of miRNA in stem cells / K. Szulwach [and others] -- Identification of cellular targets for virally-encoded miRNAs by ectopic expression and gene expression profiling / M.A. Samols, R.L. Skalsky and R. Renne -- MicroRNA in neuropsychiatric diseases / E.I. Rogaev, D.V. Islamgulov and A.P. Grigorenko -- Role of repeat-associated MicroRNA (ramRNA) in fragile X syndrome (FXS) / S.-L. Lin and S.-Y. Ying -- miRNA and schizophrenia / D.O. Perkins and C.D. Jeffries -- SNPs in microRNA and microRNA target sites associated with human cancers / S.-H. Shen and Z. Yu -- Expression and function of microRNAs in chronic myeloid leukemia / M. Scherr, L. Venturini and M. Eder -- MicroRNAs in vascular neointimal lesion formation / C. Zhang -- MicroRNA in cutaneous wound healing / C.K. Sen and S. Roy -- CpG island hypermethylation, miRNAs, and human cancer / A. Lujambio and M. Esteller -- Microarray profiling of microRNA changes in cells that express HIV-1 proteins / M.L. Yeung and K.-T. Jeang -- microRNA-associated therapies / A. Saumet [and others] -- The use of RNAi to elucidate and manipulate secondary metabolite synthesis in plants / G.J. Wagner and A.B. Kroumova
Summary Nearly 97% of the human genome is the non-coding DNA, which varies from one species to another, and changes in these sequences are frequently noticed to manifest clinical and circumstantial malfunction. Numerous non-protein-coding genes are recently found to encode microRNAs, which are responsible for RNA-mediated gene silencing through RNA interference (RNAi)-like pathways. MicroRNAs (miRNAs), small single-stranded 17a "25 nucleotide RNAs capable of interfering with intracellular messenger RNAs (mRNAs) that contain either complete or partial complementarity, are useful for the design of
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Small interfering RNA.
Gene silencing.
Non-coding RNA.
Small interfering RNA -- Therapeutic use
RNA, Small Interfering
RNA, Untranslated
Sciences de la vie.
Gene silencing.
Non-coding RNA.
Small interfering RNA.
Form Electronic book
Author Ying, Shao-Yao
ISBN 9781402085338