Microbial Status and Genetic Evaluation of Mice and Rats : Proceedings of the 1999 US/Japan Conference / International Committee of the Institute for Laboratory Animal Research ; National Research Council
Front Matter -- Preface -- Contents -- Opening Remarks -- Introductory Comments on Microbiologic Testing of Laboratory Mice and Rats: Uniformity of Results -- Development of a Performance Assessment Program for Research Animal Diagnostic Laboratories and Defining Microbiologic Testing Standards -- Standardization of Rodent Health Surveillance: Regulation Versus Competition -- Factors Causing Difficulties in Uniformity of Results Among Testing Facilities in Microbiologic Monitoring of Laboratory Animals
Necessity of Reexamining the Pathogenicity and Elimination of Parasites in Rats and MiceEmerging (and Reemerging) Viruses of Laboratory Mice and Rats -- Emerging Infections as a Cause of Concern -- Emerging Diseases in Mice and Rats -- Survey of Helicobacter Species in Laboratory Mice and Gerbils in Japan -- Genetic Evaluation of Outbred Rats -- Genetic Evaluation of Outbred Rats from the Breeder�s Perspective -- Concept for Establishment of Rat Outbred Global Standard Strains
Necessity of Genetic and Microbiologic Quality Network from the Pharmaceutical Industry�s PerspectiveInternational Harmonization of Laboratory Animals -- Rat Genetics and Toxicology -- A Phenotype-driven Approach to the Molecular and Functional Analysis of the Mouse Genome -- Evaluation of Targeted Mutations -- Defining Behavioral Phenotypes in Transgenic and Knockout Mice -- Defining Phenotype in Genetically Engineered Mice -- Development of the Mouse Model Dramatype for Human Clinical Benefit -- Concluding Remarks
Implication of Wild-derived Genes, Mitochondria, and Chromosomes in the Genetic Background of Mouse Models for Diseases and Biologic FunctionsConcluding Comments -- Concluding Comments -- Appendix A U.S./Japan Meeting November 15, 1999 Agenda -- Appendix B Meeting Participants
