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E-book

Title Hormone receptors in breast cancer / Suzanne A.W. Fuqua, editor
Published New York ; London : Springer, ©2009

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Description 1 online resource (x, 281 pages) : illustrations (some color)
Series CTAR ; v. 312
C.T.A.R. ; v. 312
Cancer treatment and research ; v. 312
Contents Hormone Action and Clinical Significance of the Estrogen Receptor [alpha] / Matthew H. Herynk, Jennifer Selever, Janagi Thirugnanasampanthan, Yukun Cui, and Suzanne A.W. Fuqua -- Role of ER in Clinical Breast Cancer / Valerie Speirs and Abeer M. Shaaban -- Hormone Action and Breast Cancer / Ellis R. Levin -- Estrogen Receptors in Breast Tumors of African American Patients / Indira Poola -- BRCA1 Cross-Talk with Hormone Receptors / Eliot M. Rosen, Yongxian Ma, and Saijun Fan -- Metastasis of Hormone Receptor Positive Breast Cancer / Monica M. Richert and Danny R. Welch -- Endocrine Therapy with Selective Estrogen Receptor Modulators (SERMs) and Aromatase Inhibitors in the Prevention and Adjuvant Therapy Settings / Shelly S. Lo, Kathleen I. Pritchard, Patricia Robinson, and Kathy S. Albain -- Biomarkers in Neoadjuvant Trials / Regina M. Fearmonti, Khandan Keyomarsi, and Kelly K. Hunt -- Hormone Resistance / Stephen R.D. Johnston -- Strategies of Hormonal Prevention / Yuxin Li and Powel H. Brown -- Estrogen Receptor Phenotypes Defined by Gene Expression Profiling / Marleen Kok, Sabine Linn, and Marc van de Vijver
Summary This book provides an up-to-date resource of the role of hormone receptors in breast cancer written in depth for both the basic molecular academic researcher and translational scientist. Advances in basic science of molecular endocrinology have undoubtedly been translated into clinical practice, and clinicians caring for this disease need to be knowledgeable about these developments. The molecular basis of hormone action has been elucidated, and the relative significance of the different estrogen and progesterone receptor isoforms has been explored. This explosion of information has led to exciting new areas of gene specific targeting of the disease, and breast cancer prevention. Paradigm shifts in treatment options and sequencing have recently occurred in breast cancer management, necessitating close cooperation and communication between translational scientists and physicians. Hormone Receptors in Breast Cancer focuses on providing this communication. "Hormones play an essential role in both the development of breast cancer and its therapy. This text provides a comprehensive review of the key receptors and signaling pathways that effect breast cancer growth leading figures in the field provide insight into the basic biology and clinical issues relevant to this devastating disease." Steven T. Rosen, MD, Series Editor
Analysis geneeskunde
medicine
volksgezondheid
public health
hematologie
haematology
endocrinologie
endocrinology
oncologie
oncology
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Breast -- Cancer -- Hormone therapy
Hormone receptors.
Cell receptors.
Breast Neoplasms -- therapy
Breast Neoplasms -- prevention & control
Receptors, Cell Surface
MEDICAL -- Oncology.
HEALTH & FITNESS -- Diseases -- Cancer.
Cell receptors
Breast -- Cancer -- Hormone therapy
Hormone receptors
Tumeurs du sein -- thérapie.
Récepteurs de surface cellulaire.
Sein -- Cancer -- Hormonothérapie.
Hormones -- Récepteurs.
Form Electronic book
Author Fuqua, Suzanne A. W.
ISBN 9780387094632
0387094636