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E-book

Title Textbook of receptor pharmacology / edited by John C. Foreman, Torben Johansen
Edition 2nd ed
Published Boca Raton, Fla. : CRC Press, ©2003

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Description 1 online resource (289 pages) : illustrations
Contents Drug-Receptor Interactions; Classical Approaches to the Study of Drug-Receptor Interactions, D.H. Jenkinson; ; Molecular Structure of Receptors; Molecular Structure and Function of 7TM G-Protein Coupled Receptors, T.W. Schwartz and B. Holst; The Structure of Ligand-Gated Ion Channels, J. Egebjerg; Molecular Structure of Receptor Tyrosine Kinases, S. Gammeltoft New!; ; Ligand Binding Studies of Receptors; Direct Measurement of Drug Binding to Receptors, D.G. Haylett; ; Transduction of the Receptor Signal; Receptors Linked to Ion Channels: Mechanisms of Activation and Block, A.J. Gibb; G Proteins, D.A. Brown New!; Signal Transduction through Protein Tyrosine Kinases, I. Kramer; ; Receptors as Pharmaceutical Targets; Receptors as Pharmaceutical Targets, J.W. Black; ; Index
Summary The bestselling first edition of Textbook of Receptor Pharmacology originated from a renowned course in receptor pharmacology taught at the University College of London for the past three decades. Its innovative format united four major approaches to the study of receptors: molecular biology, quantitative functional studies of agonists and antagonists, ligand binding, and signal transduction systems. The second edition builds on this foundation. This edition streamlines the material and focuses on cell membrane receptors along with their immediate signal transducers. The section on the molecular structure of receptors reflects the advances in this area. This edition also includes two restructured new chapters, one on G-proteins and one on tyrosine kinases, as signal transductors. Several chapters also contain problems for students to solve as well as worked-out solutions. The book contains over one hundred useful diagrams and tables to aid illustration of concepts and a helpful appendix explaining the simple mathematics used in the text. A time-saving resource and comprehensive textbook, Textbook of Receptor Pharmacology, Second Edition provides in-depth, up-to-date coverage of this still rapidly expanding research area that is both fundamental to the science of pharmacology and on the cutting edge of new drug development
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Drug receptors.
Receptors, Drug -- agonists
Receptors, Drug -- antagonists & inhibitors
Radioligand Assay -- methods
Receptors, Drug -- physiology
Signal Transduction -- physiology
Receptors, Drug
MEDICAL -- Pharmacology.
Drug receptors
Receptoren.
Geneesmiddelen.
Farmacologie.
Form Electronic book
Author Foreman, John C
Johansen, Torben
ISBN 142004107X
9781420041071
9780849310294
0849310296