| Description |
1 online resource (xvi, 672 pages) : illustrations |
| Contents |
The development of animal cell products / J.B. Griffiths -- Water quality / P. Whitehead -- Basal media and serum-free culture / David Jayme -- Serum / Richard Festen -- Recombinant products from mammalian cells / S. Jeffs -- Recombinant viral vaccines / S. jeffs -- Baculovirus expression systems / C. Mannix -- Cell cloning and stability / L. Barnes -- Gene therapy products / A. Meager -- Culture vessels and matrices for scale-up / J.M. Davis -- Process design and development / D. Robinson & E. Chu -- Facilities / S. Vranche -- Strategies for process control / T. Stoll -- Service and equipment for upstream processing / T. Stoll -- Validation of facilities & equipment / N. Chesterton and J. Davis -- Cell harvesting and clarification of culture supernatants / J. Bender -- Protein concentration / Jean Bender -- Chromatographic purification / M. Wilson -- Virus clearance/inactivation / P. Roberts -- Formulation and freeze-drying / P. Matejschuk and P. Phillips -- Preservation of cells and tissue / R. Fleck & B. Fuller -- From gene to product : an overview / J. Birch and K. Baker -- Protein analysis / K. Baker and S. Flatman -- Glycosylation of medicinal products / E. Tarelli -- Immunogenicity of cell derived vaccines / Michele Duchene -- Potency testing / D. Sesardic -- Stability of product on storage / P. Matejtscuk and P. Phillips -- Tissue engineering / T. Hardingham et al -- Stem cell therapy / Bernat Soria et al -- Cells as vaccines / Dalgleish and Whelan -- Risk assessment of cells and processes / G. Stacey -- Standardisation of cell cultures / G. Stacey -- GLP for cell culture processes / B. Orton -- GMP for cell culture processes / G. Sharp -- International regulatory framework / R. Gunther -- Legal and ethical issues for cell therapy / Lincoln Tsang |
| Summary |
Medicines from Animal Cell Culture focuses on the use of animal cell culture, which has been used to produce human and veterinary vaccines, interferon, monoclonal antibodies and genetically engineered products such as tPA and erythropoietin.℗¡It also addresses the recent dramatic expansion in cell-based therapies, including the use of live cells for tissue regeneration and the culture of stem cells. Medicines from Animal Cell Culture:.:.; Provides comprehensive descriptions of methods for cell culture and nutrition as well as the technologies for the preservation and characterisation of both th |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Animal cell biotechnology.
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Pharmaceutical biotechnology.
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Recombinant proteins -- Therapeutic use.
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Stem cells -- Transplantation.
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Biotechnology -- methods.
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Cell Culture Techniques -- methods.
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Drug Compounding -- methods.
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| Form |
Electronic book
|
| Author |
Davis, John, 1952-
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Stacey, G. (Glyn)
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Wiley InterScience (Online service)
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| ISBN |
0470723785 |
|
0470723793 |
|
0470850949 |
|
9780470723784 |
|
9780470723791 |
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9780470850947 |
|
