| Description |
1 online resource (xvi, 146 pages) : illustrations (some color) |
| Series |
Advances in experimental medicine and biology ; v. 702 |
|
Advances in experimental medicine and biology ; v. 702.
|
| Contents |
Finding the exosome / Phil Mitchell and David Tollervey -- Structural components and architectures of RNA exosomes / Kurt Januszyk and Christopher D. Lima -- The Archaeal exosome / Elena Evguenieva-Hackenberg -- The exosomes of trypanosomes and other protists / Christine Clayton and Antonio Estevez -- The exosome and 3'-5' RNA degradation in plants / Heike Lange -- Catalytic properties of the eukaryotic exosome / Aleksander Chlebowski [and others] -- Functions of the cytoplasmic exosome / Daneen Schaeffer [and others] -- Rrp6, Rrp477 and cofactors of the nuclear exosome / J. Scott Butler and Phil Mitchell -- The exosome and heterochromatin : Multilevel regulation of gene silencing / Sarah Coy and Lidia Vasiljeva -- Control of cryptic transcription in eukaryotes / Mathieu Rougemaille and Domenico Libri -- The human exosome and disease / Raymond H.J. Staals and Ger J.M. Pruijn |
| Summary |
"The diversity of RNAs inside living cells is amazing. We have known of the more "classic" RNA species: mRNA, tRNA, rRNA, snRNA and snoRNA for some time now, but in a steady stream new types of molecules are being described as it is becoming clear that most of the genomic information of cells ends up in RNA. To deal with the enormous load of resulting RNA processing and degradation reactions, cells need adequate and efficient molecular machines. The RNA exosome is arising as a major facilitator to this effect. Structural and functional data gathered over the last decade have illustrated the biochemical importance of this multimeric complex and its many co-factors, revealing its enormous regulatory power. By gathering some of the most prominent researchers in the exosome field, it is the aim of the book to introduce this fascinating protein complex and to give a timely and rich account of its many functions"--Provided by publisher |
| Analysis |
geneeskunde |
|
medicine |
|
biomedische wetenschappen |
|
biomedicine |
|
Medicine (General) |
|
Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
|
Print version record |
| In |
Springer eBooks |
| Subject |
Ribonucleases.
|
|
RNA -- Metabolism.
|
|
Ribosomes.
|
|
Exoribonucleases
|
|
RNA -- metabolism
|
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RNA Stability
|
|
Ribonucleases
|
|
Ribosomes
|
|
Ribonucleases
|
|
Ribosomes
|
|
RNA -- Metabolism
|
| Form |
Electronic book
|
| Author |
Jensen, Torben Heick, 1965-
|
| ISBN |
9781441978417 |
|
1441978410 |
|
