Description |
1 online resource (xxii, 227 pages) : illustrations (some color) |
Series |
Advances in experimental medicine and biology ; v. 642 |
|
Advances in experimental medicine and biology ; v. 642.
|
Contents |
880-01 The sarcomere and sarcomerogenesis / Elisabeth Ehler and Mathias Gautel -- Skeletal muscle alpha-actin diseases / Kathryn N. North and Nigel G. Laing -- Nebulin : a giant chameleon / Katarina Pelin and Carina Wallgren-Pettersson -- Skeletal muscle disease due to mutations in tropomyosin, troponin and cofilin / Nigel F. Clarke -- Investigations into the pathobiology of thin-filament myopathies / Biljana Ilkovski -- Mouse models for thin filament disease / Mai-Anh T. Nguyen and Edna C. Hardeman -- Thick filament diseases / Anders Oldfors and Phillipa J. Lamont -- Acute quadriplegic myopathy : an acquired "myosinopathy" / Lars Larsson -- Third filament diseases / Bjarne Udd -- The Z-disk diseases / Duygu Selcen and Olli Carpén -- Intermediate filament diseases : desminopathy / Lev G. Goldfarb [and others] -- Muscular integrity : a matter of interlinking distinct structures via plectin / Patryk Konieczny and Gerhard Wiche -- The sarcomere and the nucleus : functional links to hypertrophy, atrophy and sarcopenia / Mathias Gautel -- Other model organisms for sarcomeric muscle diseases / John Sparrow, Simon M. Hughes and Laurent Segalat -- Therapeutic approaches for the sarcomeric protein diseases / Kristen J. Nowak |
|
880-01/(Q The sarcomere and sarcomerogenesis / Elisabeth Ehler and Mathias Gautel -- Skeletal muscle alpha-actin diseases / Kathryn N. North and Nigel G. Laing -- Nebulin : a giant chameleon / Katarina Pelin and Carina Wallgren-Pettersson -- Skeletal muscle disease due to mutations in tropomyosin, troponin and cofilin / Nigel F. Clarke -- Investigations into the pathobiology of thin-filament myopathies / Biljana Ilkovski -- Mouse models for thin filament disease / Mai-Anh T. Nguyen and Edna C. Hardeman -- Thick filament diseases / Anders Oldfors and Phillipa J. Lamont -- Acute quadriplegic myopathy : an acquired "myosinopathy" / Lars Larsson -- Third filament diseases / Bjarne Udd -- The Z-disk diseases / Duygu Selcen and Olli Carpe⁺ѓn -- Intermediate filament diseases : desminopathy / Lev G. Goldfarb [and others] -- Muscular integrity : a matter of interlinking distinct structures via plectin / Patryk Konieczny and Gerhard Wiche -- The sarcomere and the nucleus : functional links to hypertrophy, atrophy and sarcopenia / Mathias Gautel -- Other model organisms for sarcomeric muscle diseases / John Sparrow, Simon M. Hughes and Laurent Segalat -- Therapeutic approaches for the sarcomeric protein diseases / Kristen J. Nowak |
Summary |
Although best known for its role in heart disease, the sarcomere--the fundamental unit of muscle contraction--is also involved in skeletal muscle diseases. Chapters in The Sarcomere and Skeletal Muscle Disease provide an up-to-date review of diseases caused by mutated proteins in the different sub-compartments of the sarcomere, document the techniques currently being used to investigate the pathobiological bases of the diseases, which remain largely unknown, and discuss possible therapeutic options |
Bibliography |
Includes bibliographical references and index |
Subject |
Muscles -- Diseases.
|
|
Muscular Diseases
|
|
Muscle, Skeletal -- physiopathology
|
|
Sarcomeres
|
|
MEDICAL -- Orthopedics.
|
|
HEALTH & FITNESS -- Diseases -- Musculoskeletal.
|
|
MEDICAL -- Rheumatology.
|
|
Muscular Diseases.
|
|
Muscle, Skeletal -- physiopathology.
|
|
Sarcomeres.
|
|
Muscles -- Diseases.
|
|
Biomédecine.
|
|
Sciences de la vie.
|
|
Muscles -- Diseases
|
Form |
Electronic book
|
Author |
Laing, Nigel G.
|
ISBN |
9780387848464 |
|
0387848460 |
|
9780387848471 |
|
0387848479 |
|