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Title Mechanisms of sepsis-induced organ dysfunction and recovery / E. Abraham, M. Singer (eds.)
Published Berlin ; New York : Springer, ©2007


Description 1 online resource (xiii, 453 pages) : illustrations
Series Update in intensive care and emergency medicine, 0933-6788 ; 44
Update in intensive care and emergency medicine ; 44. 0933-6788
Contents Setting the Scene / J.L. Vincent -- The Inflammatory Response. Genetics and Severe Sepsis / J. Texereau, V. Lemiale, J.-P. Mira ; Cell Signaling Pathways of the Innate Immune System During Acute Inflammation / S.M. Opal, P.A. Cristofaro ; Early-Onset Pro-inflammatory Cytokines / C. Kaech, T. Calandra ; The Significance of HMGB1, a Late-Acting Pro-inflammatory Cytokine / E. Abraham ; Nitric Oxide / J. Carré, M. Singer, S. Moncada ; Involvement of Reactive Oxygen and Nitrogen Species in the Pathogenesis of Acute Lung Injury / S. Matalon, I.C. Davis, J.D. Lang Jr ; Heat Shock Proteins in Inflammation / Z. Bromberg, Y.G. Weiss, C.S. Deutschman ; Fibrosis in the Acute Respiratory Distress Syndrome / D.C.J. Howell, R.C. Chambers, G.J. Laurent ; Resolution of Inflammation. / G. Bellingan -- The Cellular Immune Respone. Compartmentalized Activation of Immune Cells During Sepsis and Organ Dysfunction / J.-M. Cavaillon, M. Adib-Conquy ; The Neutrophil in the Pathogenesis of Multiple Organ Dysfunction Syndrome / Z. Malam, J.C. Marshall ; The Role of the Macrophage / J. Pugin ; The Role of the Endothelium / W.C. Aird ; Differential Effects of Pro-Inflammatory Mediators on Alveolar Epithelial Barrier Function / M.A. Matthay, J.-W. Lee -- Mechanisms and Pathways of Dysfunction. Macrocirculatory Disturbances / D. De Backer ; The Microcirculation Is a Vulnerable Organ in Sepsis / P.W.G. Elbers, C. Ince ; The Cholinergic Anti-inflammatory Pathway: Connecting the Mind and Body / C.J. Czura, S.G. Friedman, K.J. Tracey ; Coagulation in Sepsis / W.J. Wiersinga, M. Levi, T. van der Poll ; The Role of Insulin and Blood Glucose Control / L. Langouche, I. Vanhorebeek, G. Van den Berghe ; Dysfunction of the Bioenergetic Pathway / M. Singer ; Metabolic Pathways / O. Rooyackers, J. Wernerman ; Cell Death and Acute Lung Injury / T.R. Martin, N. Hagimoto, G. Matute-Bello ; Mechanisms of Immunodepression after Central Nervous System Injury / C. Meisel, H.-D. Volk -- Organ-specific Mechanisms of Dysfunction. Pulmonary Dysfunction / N.S. MacCallum, G.J. Quinlan, T.W. Evans ; The Gut / M.P. Fink ; Endogenous Danger Signals in Liver Injury: Role of High Mobility Group Box Protein-1 / A. Tsung, G. Jeyabalan, T.R. Billiar ; Sepsis-induced Acute Renal Failure and Recovery / M. Raghavan, R. Venkataraman, J.A. Kellum ; Sepsis-Induced Brain Dysfunction / C. Guidoux, T. Sharshar, D. Annane ; Myocardial Depression in Sepsis and Septic Shock / A. Kumar, J.E. Parrillo ; Skeletal Muscle / R.D. Griffiths, T. Bongers, A. McArdle
Summary There have been tremendous advances in understanding the cellular mechanisms involved in sepsis and contributing to the development of multiple organ dysfunction and mortality in this setting. The chapters in this book provide up-to-date insights into important pathways that are initiated by sepsis
Analysis geneeskunde
public health
intensive care
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references and index
Notes Print version record
In Springer e-books
Subject Multiple organ failure.
Septicemia -- Pathophysiology
Sepsis -- complications
Multiple Organ Failure
Critical Care -- methods
Multiple Organ Failure -- etiology
MEDICAL -- Infectious Diseases.
HEALTH & FITNESS -- Diseases -- Contagious.
Critical care -- Methods.
Multiple Organ Failure -- etiology.
Multiple organ failure.
Septicemia -- Pathophysiology.
Sepsis -- complications.
Multiple organ failure.
Septicemia -- Pathophysiology.
Form Electronic book
Author Abraham, Edward.
Singer, Mervyn.
ISBN 9783540303282