Description |
1 online resource (viii, 280 pages, 4 pages) of plates : illustrations ; cm |
Series |
Novartis Foundation symposium ; 262 |
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Novartis Foundation symposium ; 262
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Contents |
Machine derived contents note: Chair's Introduction (Leroith). -- Circulating IGF-I and its role in cancer: lessons from the IGF-1 gene-deletion (LID) mouse (Yakar et al). -- Physiology of the IGF system (Holly). -- Molecular basis of insulin action (Zick). -- IGF-1 and insulin as growth hormones (Laron). -- Insulin-like growth factors and neoplasia (Pollak). -- Loss of IGF2 imprinting: mechanisms and consequences (Ohlsson). -- Insulin and IGF-1 receptor trafficking and sginalling (Foti et al). -- The mTOR/S6K signalling pathway: the role of the TSC1/2 tumour suppressor complex and the proto-oncogene Rheb (Nobukini and Thomas). -- Structural biology of insulin and IGF-1 receptors (De Meyts et al). -- Genetic blockade of the insulin-like growth factor-I receptor for human malignancy (Adachi et al). -- IGF-1 and prostate cancer (Roberts Jr.). -- IGF-1 and breast cancer (Lonning and Helle). -- IGFBPs and cancer (Fang et al). -- The IGF receptor as anti-cancer treatment target (Macaulay). -- Nutrition, insulin, IGF-1 metabolism and cancer risk: a summary of epidemiological evidence (Kaaks). -- Final discussion. -- Index of contributors. -- Subject index |
Analysis |
Chemical Biology and Biochemistry |
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ER Internet Book Full text |
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FACsci |
Bibliography |
Includes bibliographical references and index |
Subject |
Carcinogenesis -- Congresses.
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Somatomedin -- Pathophysiology -- Congresses.
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Somatomedin -- Physiological effect -- Congresses.
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Genre/Form |
Conference papers and proceedings.
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Form |
Electronic book
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Author |
Bock, Gregory.
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Goode, Jamie.
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John Wiley & Sons.
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Wiley InterScience (Online service)
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ISBN |
0470869976 (electronic bk.) |
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0470869984 (alk. paper) |
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