| Description |
1 online resource (xvii, 262 pages) : illustrations |
| Series |
Stem cell biology and regenerative medicine |
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Stem cell biology and regenerative medicine.
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| Contents |
Foreword -- Part I -- Germline developmental potential -- 1. Primordial germ cells to EG cells, Peter Donovan -- 2. Pluripotent stem cells from SSCs, Marco Seandel, Ilaria Falciatori, and Shahin Rafii -- 3. ES cells to gametes, Sonya M. Schuh-Huerta and Renee A. Reijo Pera -- Part II -- Spermatogonial stem cells -- 4. Morphometric description of the SSC pool in mammals, Dirk G. de Rooij -- 5. Spermatogonial stem cell transplantation and culture, Jonathan A. Schmidt and Ralph L. Brinster -- 6. Spermatogonial stem cell culture and in vitro assay, Makoto C. Nagano and Jonathan R. Yeh -- 7. Molecular signaling in SSCs, Olga M. Ocón-Grove and Jon M. Oatley -- 8. Spermatogonial stem cell niche, Shosei Yoshida -- Part III -- Translation and regenerative potential of spermatogonial stem cells in higher primates -- 9. Gonadotoxic therapies: effects on spermatogenesis and fertility, Gunapala Shetty, Gensheng Wang, and Marvin L. Meistrich -- 10. Testicular xenografting, Stefan Schlatt, Jose R Rodriguez-Sosa and Ina Dobrinski -- 11. SSC transplantation in primates, Brian P. Hermann and Kyle E. Orwig |
| Summary |
Scientists investigating germ cells have, over the past 15 years, originated discoveries and innovations that give us valuable insights into the mechanisms that regulate not just stem cell function, but human development in its widest sense. With contributions from some of the leading researchers in the field, "Male Germline Stem Cells: Developmental and Regenerative Potential" assesses the implications of these discoveries for understanding the fundamental biology of germline stem cells as well as their potential for human stem cell-based therapies. This monograph covers many of the |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
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Print version record |
| Subject |
Germ cells.
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Stem cells.
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Regenerative medicine.
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Stem Cells
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Spermatogonia
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Germ Cells
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Regenerative Medicine
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MEDICAL -- Research.
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Stem cells
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Regenerative medicine
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Germ cells
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| Form |
Electronic book
|
| Author |
Orwig, Kyle E
|
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Hermann, Brian P
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| ISBN |
9781617379734 |
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1617379735 |
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9781617379727 |
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1617379727 |
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