| Description |
1 online resource (484 pages) |
| Series |
CRC revivals |
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CRC revivals.
|
| Contents |
Cover -- Title -- Copyright -- EDITORS -- CONTRIBUTORS -- Contents -- Chapter 1 Steroid Structure and Function from X-Ray Crystallographic Studies -- Chapter 2 1H and 13C NMR Spectroscopy of Sterols -- Chapter 3 Theoretical Investigations on Steroid Structure and Quantitative Structure-Activity Relationships -- Chapter 4 Two Approaches to Structure-Activity Relationships in the Field of Sex Steroids and Their Analogs -- Chapter 5 Stilbestrol Estrogens: Molecular/Structural Probes for Understanding Estrogen Action -- Chapter 6 Aromatase: Mechanism and Inhibition -- Chapter 7 Structure-Activity Relationships of Glucocorticoids: Importance of the Regulated Gene and Trans-Acting Factors in Determining Glucocorticoid and Antiglucocorticoid Activity -- Chapter 8 Molecular Structure and Biological Activity of Vitamin D Metabolites and Their Analogs -- Chapter 9 Molecular Structure and Biological Activity of Brassinolide and Related Brassinosteroids -- Chapter 10 Structure-Activity Relationships of Androgens and Anabolics -- Chapter 11 Structure-Activity Relationships of Steroidal Neuromuscular Blocking Agents -- Chapter 12 Molecular Biology of Cardiotonic Steroids -- Index |
| Summary |
"Molecular Structure and Biological Activity of Steroids focuses on the indentification of steroid structural features that control particular biological effects. Steroid geometry plays a critical role in steroid activity; therefore, the results of X-ray crystallographic, NMR spectroscopic, and theoretical studies on structure-activity relationships form an integral part of the book. Well-established observations and proposed models are presented, summarizing knowledge of molecular features (e.g., steroid backbone structures, side-chain constitutions, substitution sites, configurations, hydrogen-bonding patterns) that can affect steroid action. The book also provides overviews about recent progress in various frontier fields of steroid research, including such areas as sex steroids, glucocorticoids, aromatase inhibitors, vitamin D metabolites, brassinosteroids, neuromuscular blocking agents, and cardiotonic steroids. Molecular Structure and Biological Activity of Steroids is a "must-have" resource for biochemists, pharmacologists, endocrinologists, biophysicists, and others actively involved in steroid research."--Provided by publisher |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from PDF title page (EBSCO, viewed February 12, 2018) |
| Subject |
Steroids -- Structure-activity relationships
|
|
MEDICAL -- Physiology.
|
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SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
|
| Form |
Electronic book
|
| Author |
Bohl, Martin, editor.
|
|
Duax, William L., 1939- editor.
|
| ISBN |
9781351074803 |
|
1351074806 |
|
