Limit search to available items
Nearby Subjects are:
Result Page   Prev Next
Add Marked to Bag Add All On Page Add Marked to My Lists
Mark   Year Entries
 

T. C. (Thomas Churchyard), 1520?-1604 -- See Churchyard, Thomas, 1520?-1604


  1
 

T.C. (Türkiye Cumhuriyeti) -- See Turkey


  1
 

T-Cell -- See T-Lymphocytes


Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen
  1
 

T-Cell Antigen Receptor -- See Receptors, Antigen, T-Cell


Molecules on the surface of T-lymphocytes that recognize and combine with antigens. The receptors are non-covalently associated with a complex of several polypeptides collectively called CD3 antigens (CD3 COMPLEX). Recognition of foreign antigen and the major histocompatibility complex is accomplished by a single heterodimeric antigen-receptor structure, composed of either alpha-beta (RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA) or gamma-delta (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA) chains
  1
T-Cell Antigen Receptor Specificity : Analyzing T cell responses : how to analyze cellular immune responses against tumor associated antigens / edited by Dirk Nagorsen and F.M. Marincola  2005 1
 

T-Cell Antigen Receptors -- See Receptors, Antigen, T-Cell


Molecules on the surface of T-lymphocytes that recognize and combine with antigens. The receptors are non-covalently associated with a complex of several polypeptides collectively called CD3 antigens (CD3 COMPLEX). Recognition of foreign antigen and the major histocompatibility complex is accomplished by a single heterodimeric antigen-receptor structure, composed of either alpha-beta (RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA) or gamma-delta (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA) chains
  1
 

T-Cell, CD8-Positive Suppressor -- See CD8-Positive T-Lymphocytes


A critical subpopulation of regulatory T-lymphocytes involved in MHC Class I-restricted interactions. They include both cytotoxic T-lymphocytes (T-LYMPHOCYTES, CYTOTOXIC) and CD8+ suppressor T-lymphocytes
  1
 

T cell differentiation -- See T cells Differentiation


  1
 

T-Cell Factors -- See TCF Transcription Factors


A family of DNA-binding proteins that are primarily expressed in T-LYMPHOCYTES. They interact with BETA CATENIN and serve as transcriptional activators and repressors in a variety of developmental processes
  1
 

T cell growth factor -- See Interleukin-2


  1
 

T-Cell Growth Factor Receptor -- See Receptors, Interleukin-2


Receptors present on activated T-LYMPHOCYTES and B-LYMPHOCYTES that are specific for INTERLEUKIN-2 and play an important role in LYMPHOCYTE ACTIVATION. They are heterotrimeric proteins consisting of the INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT, the INTERLEUKIN-2 RECEPTOR BETA SUBUNIT, and the INTERLEUKIN RECEPTOR COMMON GAMMA-CHAIN
  1
 

T-Cell Growth Factor Receptors -- See Receptors, Interleukin-2


Receptors present on activated T-LYMPHOCYTES and B-LYMPHOCYTES that are specific for INTERLEUKIN-2 and play an important role in LYMPHOCYTE ACTIVATION. They are heterotrimeric proteins consisting of the INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT, the INTERLEUKIN-2 RECEPTOR BETA SUBUNIT, and the INTERLEUKIN RECEPTOR COMMON GAMMA-CHAIN
  1
 

T-Cell Immunologic Specificity -- See T-Cell Antigen Receptor Specificity


The property of the T-CELL RECEPTOR which enables it to react with some antigens and not others. The specificity is derived from the structure of the receptor's variable region which has the ability to recognize certain antigens in conjunction with the MAJOR HISTOCOMPATIBILITY COMPLEX molecule
  1
 

T-cell leukemia, Adult -- See Adult T-cell leukemia


  1
 

T-cell leukemia virus I, Human -- See HTLV-I (Virus)


  1
 

T Cell Leukemia Viruses, Human -- See Deltaretrovirus


A genus in the family RETROVIRIDAE consisting of exogenous horizontally-transmitted viruses found in a few groups of mammals. Infections caused by these viruses include human B- or adult T-cell leukemia/lymphoma (LEUKEMIA-LYMPHOMA, T-CELL, ACUTE, HTLV-I-ASSOCIATED), and bovine leukemia (ENZOOTIC BOVINE LEUKOSIS). The type species is LEUKEMIA VIRUS, BOVINE
  1
 

T-Cell Lymphoma, Cutaneous -- See Lymphoma, T-Cell, Cutaneous


A group of lymphomas exhibiting clonal expansion of malignant T-lymphocytes arrested at varying stages of differentiation as well as malignant infiltration of the skin. MYCOSIS FUNGOIDES; SEZARY SYNDROME; LYMPHOMATOID PAPULOSIS; and PRIMARY CUTANEOUS ANAPLASTIC LARGE CELL LYMPHOMA are the best characterized of these disorders
  1
 

T-Cell Lymphomas, Cutaneous -- See Lymphoma, T-Cell, Cutaneous


A group of lymphomas exhibiting clonal expansion of malignant T-lymphocytes arrested at varying stages of differentiation as well as malignant infiltration of the skin. MYCOSIS FUNGOIDES; SEZARY SYNDROME; LYMPHOMATOID PAPULOSIS; and PRIMARY CUTANEOUS ANAPLASTIC LARGE CELL LYMPHOMA are the best characterized of these disorders
  1
 

T-Cell, Naturally-Occurring Suppressor -- See T-Lymphocytes, Regulatory


CD4-positive T cells that inhibit immunopathology or autoimmune disease in vivo. They inhibit the immune response by influencing the activity of other cell types. Regulatory T-cells include naturally occurring CD4+CD25+ cells, IL-10 secreting Tr1 cells, and Th3 cells
  1
 

T-Cell Receptor -- See Receptors, Antigen, T-Cell


Molecules on the surface of T-lymphocytes that recognize and combine with antigens. The receptors are non-covalently associated with a complex of several polypeptides collectively called CD3 antigens (CD3 COMPLEX). Recognition of foreign antigen and the major histocompatibility complex is accomplished by a single heterodimeric antigen-receptor structure, composed of either alpha-beta (RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA) or gamma-delta (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA) chains
  1
 

T-Cell Receptor delta-Chain -- See Receptors, Antigen, T-Cell, gamma-delta


T-cell receptors composed of CD3-associated gamma and delta polypeptide chains and expressed primarily in CD4-/CD8- T-cells. The receptors appear to be preferentially located in epithelial sites and probably play a role in the recognition of bacterial antigens. The T-cell receptor gamma/delta chains are separate and not related to the gamma and delta chains which are subunits of CD3 (see ANTIGENS, CD3)
  1
 

T-Cell Receptor delta-Chain Genes -- See Genes, T-Cell Receptor delta


DNA sequences encoding the delta chain of the T-cell receptor. The delta-chain locus is located entirely within the alpha-chain locus
  1
 

T-Cell Receptor delta Genes -- See Genes, T-Cell Receptor delta


DNA sequences encoding the delta chain of the T-cell receptor. The delta-chain locus is located entirely within the alpha-chain locus
  1
 

T-Cell Receptor gamma-Chain -- See Receptors, Antigen, T-Cell, gamma-delta


T-cell receptors composed of CD3-associated gamma and delta polypeptide chains and expressed primarily in CD4-/CD8- T-cells. The receptors appear to be preferentially located in epithelial sites and probably play a role in the recognition of bacterial antigens. The T-cell receptor gamma/delta chains are separate and not related to the gamma and delta chains which are subunits of CD3 (see ANTIGENS, CD3)
  1
 

T-Cell Receptor gamma-Chain Genes -- See Genes, T-Cell Receptor gamma


DNA sequences encoding the gamma chain of the T-cell receptor. The human gamma-chain locus is organized similarly to the TcR beta-chain locus
  1
 

T-Cell Receptor, gamma-delta -- See Receptors, Antigen, T-Cell, gamma-delta


T-cell receptors composed of CD3-associated gamma and delta polypeptide chains and expressed primarily in CD4-/CD8- T-cells. The receptors appear to be preferentially located in epithelial sites and probably play a role in the recognition of bacterial antigens. The T-cell receptor gamma/delta chains are separate and not related to the gamma and delta chains which are subunits of CD3 (see ANTIGENS, CD3)
  1
 

T-Cell Receptor gamma Genes -- See Genes, T-Cell Receptor gamma


DNA sequences encoding the gamma chain of the T-cell receptor. The human gamma-chain locus is organized similarly to the TcR beta-chain locus
  1
 

T-Cell Receptor Gene -- See Genes, T-Cell Receptor


DNA sequences, in cells of the T-lymphocyte lineage, that code for T-cell receptors. The TcR genes are formed by somatic rearrangement (see GENE REARRANGEMENT, T-LYMPHOCYTE and its children) of germline gene segments, and resemble Ig genes in their mechanisms of diversity generation and expression
  1
 

T-Cell Receptor Genes -- See Genes, T-Cell Receptor


DNA sequences, in cells of the T-lymphocyte lineage, that code for T-cell receptors. The TcR genes are formed by somatic rearrangement (see GENE REARRANGEMENT, T-LYMPHOCYTE and its children) of germline gene segments, and resemble Ig genes in their mechanisms of diversity generation and expression
  1
T-cell receptor genes. : The T cell receptor factsbook / Marie-Paule Lefranc, Gérard Lefranc  2001 1
T-cell receptor genes -- Handbooks, manuals, etc : The T cell receptor factsbook / Marie-Paule Lefranc, Gérard Lefranc  2001 1
 

T-Cell Receptor Specificity -- See T-Cell Antigen Receptor Specificity


The property of the T-CELL RECEPTOR which enables it to react with some antigens and not others. The specificity is derived from the structure of the receptor's variable region which has the ability to recognize certain antigens in conjunction with the MAJOR HISTOCOMPATIBILITY COMPLEX molecule
  1
  T-Cell Receptors -- 2 Related Subjects   2
 

T-Cell Receptors, Costimulatory -- See Costimulatory and Inhibitory T-Cell Receptors


A family of receptors that modulate the activation of T-LYMPHOCYTES by the T-CELL ANTIGEN RECEPTOR. The receptors are responsive to one or more B7 ANTIGENS found on ANTIGEN-PRESENTING CELLS and, depending upon the specific ligand-receptor combination, modulate a variety of T-cell functions such as the rate of clonal expansion, CELL SURVIVAL and cytokine production. Although commonly referred to as costimulatory receptors, some of the receptors have inhibitory effects such as inducing PERIPHERAL TOLERANCE
  1
 

T-Cell Receptors delta-Chain -- See Receptors, Antigen, T-Cell, gamma-delta


T-cell receptors composed of CD3-associated gamma and delta polypeptide chains and expressed primarily in CD4-/CD8- T-cells. The receptors appear to be preferentially located in epithelial sites and probably play a role in the recognition of bacterial antigens. The T-cell receptor gamma/delta chains are separate and not related to the gamma and delta chains which are subunits of CD3 (see ANTIGENS, CD3)
  1
 

T-Cell Receptors gamma-Chain -- See Receptors, Antigen, T-Cell, gamma-delta


T-cell receptors composed of CD3-associated gamma and delta polypeptide chains and expressed primarily in CD4-/CD8- T-cells. The receptors appear to be preferentially located in epithelial sites and probably play a role in the recognition of bacterial antigens. The T-cell receptor gamma/delta chains are separate and not related to the gamma and delta chains which are subunits of CD3 (see ANTIGENS, CD3)
  1
 

T Cell Receptors, gamma delta -- See Receptors, Antigen, T-Cell, gamma-delta


T-cell receptors composed of CD3-associated gamma and delta polypeptide chains and expressed primarily in CD4-/CD8- T-cells. The receptors appear to be preferentially located in epithelial sites and probably play a role in the recognition of bacterial antigens. The T-cell receptor gamma/delta chains are separate and not related to the gamma and delta chains which are subunits of CD3 (see ANTIGENS, CD3)
  1
 

T-Cell Receptors, Inhibitory -- See Costimulatory and Inhibitory T-Cell Receptors


A family of receptors that modulate the activation of T-LYMPHOCYTES by the T-CELL ANTIGEN RECEPTOR. The receptors are responsive to one or more B7 ANTIGENS found on ANTIGEN-PRESENTING CELLS and, depending upon the specific ligand-receptor combination, modulate a variety of T-cell functions such as the rate of clonal expansion, CELL SURVIVAL and cytokine production. Although commonly referred to as costimulatory receptors, some of the receptors have inhibitory effects such as inducing PERIPHERAL TOLERANCE
  1
 

T-Cell Specificity -- See T-Cell Antigen Receptor Specificity


The property of the T-CELL RECEPTOR which enables it to react with some antigens and not others. The specificity is derived from the structure of the receptor's variable region which has the ability to recognize certain antigens in conjunction with the MAJOR HISTOCOMPATIBILITY COMPLEX molecule
  1
 

T-Cell Therapies, CAR -- See Immunotherapy, Adoptive


Form of adoptive transfer where cells with antitumor activity are transferred to the tumor-bearing host in order to mediate tumor regression. The lymphoid cells commonly used are lymphokine-activated killer (LAK) cells and tumor-infiltrating lymphocytes (TIL). This is usually considered a form of passive immunotherapy. (From DeVita, et al., Cancer, 1993, pp.305-7, 314)
  1
 

T-Cell Therapy, CAR -- See Immunotherapy, Adoptive


Form of adoptive transfer where cells with antitumor activity are transferred to the tumor-bearing host in order to mediate tumor regression. The lymphoid cells commonly used are lymphokine-activated killer (LAK) cells and tumor-infiltrating lymphocytes (TIL). This is usually considered a form of passive immunotherapy. (From DeVita, et al., Cancer, 1993, pp.305-7, 314)
  1
  T-Cells -- 2 Related Subjects   2
T cells.   55
 

T-Cells, CD8-Positive Suppressor -- See CD8-Positive T-Lymphocytes


A critical subpopulation of regulatory T-lymphocytes involved in MHC Class I-restricted interactions. They include both cytotoxic T-lymphocytes (T-LYMPHOCYTES, CYTOTOXIC) and CD8+ suppressor T-lymphocytes
  1
T cells -- Computer simulation : Mathematical, computational and experimental T cell immunology / Carmen Molina-París, Grant Lythe, editors  2021 1
T cells -- Congresses : Animal models of T cell-mediated skin diseases / T. Zollner, H. Renz, K. Asadullah, editors  2004 1
T cells -- Differentiation   4
T cells -- Differentiation -- Laboratory manuals   2
T cells -- Immunology : Analyzing T cell responses : how to analyze cellular immune responses against tumor associated antigens / edited by Dirk Nagorsen and F.M. Marincola  2005 1
T cells -- Laboratory manuals   14
Add Marked to Bag Add All On Page Add Marked to My Lists
Result Page   Prev Next