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Title Suppression and regulation of immune responses : methods and protocols / edited by Maria Cristina Cuturi and Ignacio Anegon
Published New York, N.Y. : Humana Press, ©2011


Description 1 online resource (xviii, 473 pages) : illustrations
Series Springer protocols
Methods in molecular biology, 1940-6029 ; 677
Springer protocols (Series)
Methods in molecular biology (Clifton, N.J.) ; v. 677. 1064-3745
Contents Natural and induced T CD4+CD25+FOXP3+ regulatory T cells / L. Chatenoud -- Polyclonal expansion of human CD4(+)CD25(+) regulatory T cells / P. Hoffmann, R. Eder and M. Edinger -- Methods for in vitro generation of human type 1 regulatory T cells / S. Gregori, M.G. Roncarolo and R. Bacchetta -- Ex vivo generation of regulatory T cells: Characterization and therapeutic evaluation in a model of chronic colitis / F. Karlsson [and others] -- Phenotypic and functional characterization of CD8(+) T regulatory cells / S. Menoret [and others] -- Regulatory CD4( -- )CD8( -- ) double negative T cells / E.Y. Kim, S.C. Juvet and L. Zhang -- Identifying regulatory B cells (B10 cells) that produce IL-10 in mice / T. Matsushita and T.F. Tedder -- DCs in immune tolerance in steady-state conditions / T. Fukaya [and others] -- Plasmacytoid dendritic cells in tolerance / E. Gehrie [and others] -- In vitro-generated DC with tolerogenic functions: Perspectives for in vivo cellular therapy / C. van Kooten and K.A. Gelderman -- Preparation of mouse bone marrow-derived dendritic cells with immunoregulatory properties / M. Segovia, M.C. Cuturi and M. Hill -- Myeloid-derived suppressor cells: Characterization and expansion in models of endotoxemia and transplantation / N. Van Rompaey and A. Le Moine -- Human regulatory macrophages / J.A. Hutchinson [and others] -- NKT and tolerance / J. Diana [and others] -- Antiinflammatory and immunosuppressive functions of mast cells / J. Kalesnikoff and S.J. Galli -- A mesenchymal stem cell potency assay / J. Jiao [and others] -- In vitro analyses of the immunosuppressive properties of neural stem/progenitor cells using anti-CD3/CD28-activated T cells / V. Bonnamain, I. Neveu and P. Naveilhan -- Immunoregulatory properties of heme oxygenase-1 / P. Blancou [and others] -- Indoleamine 2,3-dioxygenase and regulatory function: Tryptophan starvation and beyond / C. Orabona and U. Grohmann -- Regulatory T cell enrichment by IFN-[gamma] conditioning / G. Feng, K.J. Wood and A. Bushell -- Transforming growth factor-beta: Recent advances on its role in immune tolerance / P.Y. Mantel and C.B. Schmidt-Weber -- Induction of tolerogenic dendritic cells by NF-[kappa]b blockade and fcgamma receptor modulation / L.J. Carreno, C.A. Riedel and A.M. Kalergis -- Fine-tuning antitumor responses through the control of galectin-glycan interactions: An overview / M. Salatino and G.A. Rabinovich -- Regulation of lymphocytes by nitric oxide / C. Bogdan -- Pregnancy: Tolerance and suppression of immune responses / A. Leber [and others] -- Organ transplantation: Modulation of t-cell activation pathways initiated by cell surface receptors to suppress graft rejection / K. Weatherly and M.Y. Braun -- Immunosuppressive mechanisms during viral infectious diseases / G. Sarikonda and M.G. von Herrath -- Ocular immune privilege sites / S. Masli and J.L. Vega -- Immunoprivileged sites: The testis / M. Fijak, S. Bhushan and A. Meinhardt
Summary Over the past several years, a high diversity of regulatory cells and suppressive molecules has taken centre stage in the field of immunoregulation. In Suppression and Regulation of Immune Responses: Methods and Protocols, expert researchers highlight recent advances in the identification, characterization, and generation of regulatory cells not only of the T cell lineage but also of other origins such as B, NK, myeloid, and dendritic cells, as well as the role of several suppressive molecules in immunoregulation. Particular emphasis is placed on the characterization of the molecular mechanisms and the therapeutic applications of regulatory cells and molecules in human diseases. Written as a volume in the highly successful Methods in Molecular Biology series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Comprehensive and cutting-edge, Suppression and Regulation of Immune Responses: Methods and Protocols serves as a key reference for scientists seeking a way toward greater control over the enormous power of the complex and vital immune system
Analysis immunologie
biomedische wetenschappen
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Immune response -- Regulation.
Biological products -- Therapeutic use.
Immune system.
T cells.
Blood cells.
Biological Therapy
Immune System Phenomena
Immunologic Techniques
Phenomena and Processes
Leukocytes, Mononuclear
Investigative Techniques
Immunosuppression Therapy
Analytical, Diagnostic and Therapeutic Techniques and Equipment
Blood Cells
Immune System
Hemic and Immune Systems
Immune Tolerance
blood (animal material)
treating (health care function)
T cells
Immune system
Blood cells
Biological products -- Therapeutic use
Immune response -- Regulation
Form Electronic book
Author Cuturi, Maria Cristina
Anegon, Ignacio
ISBN 9781607618690