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Title LC-MS in drug bioanalysis / Q. Alan Xu, Timothy L. Madden, editors
Published New York : Springer, ©2012


Description 1 online resource
Contents Internal Standards for Quantitative LC-MS Bioanalysis / Aimin Tan, Nadine Boudreau and Ann Lévesque -- Method Development, Validation, and Sample Analysis for Regulated Quantitative Bioanalysis Using LC-MS/MS / Min Meng and Patrick K. Bennett -- Impact of Sampling Paper/Cards on Bioanalytical Quantitation via Dried Blood Spots by Liquid Chromatography-Mass Spectrometry / Jun Zhang, Ramona Rodila, Huaiqin Wu and Tawakol A. El-Shourbagy -- Highly Sensitive Pharmaceutical and Clinical Analysis Using Selective Solid-Phase Extraction Coupled to Microflow Liquid Chromatography and Isotope-Dilution Mass Spectrometry / Haoying Yu, Xiaotao Duan and Jun Qu -- Pitfalls of LC-MS/MS in the Clinical Laboratory / Christoph Seger and Michael Vogeser -- Therapeutic Drug Monitoring to Support Clinical Pharmacogenomics / Alan H.B. Wu and Kara L. Lynch -- Liquid Chromatography-Mass Spectrometry for the Determination of Antidepressants and Some of their Major Metabolites in Human Biological Matrices / Ana de Castro, Angelines Cruz and Manuel López-Rivadulla -- The Analysis of Antipsychotic Drugs in Human Biosamples by LC-MS / Eva Saar, Dimitri Gerostamoulos, Olaf H. Drummer and Jochen Beyer -- Therapeutic Drug Monitoring of Targeted Anticancer Therapy. Tyrosine Kinase Inhibitors and Selective Estrogen Receptor Modulators: A Clinical Pharmacology Laboratory Perspective / Laurent Decosterd, Elyes Dahmane, Marine Neeman, Thierry Buclin and Chantal Csajka, et al. -- Applications of Mass Spectrometry in Analyses of Steroid Hormones / Zimeng Yan, Chang Cheng and Shaorong Liu -- Liquid Chromatography-Mass Spectrometric Analysis of Tropane Alkaloids in Mammalian Samples: Techniques and Applications / Harald John -- Analysis of Illicit Drugs in Human Biological Samples by LC-MSn / Manuel Sergi and Sabino Napoletano -- Use of Matrix Assisted Laser Desorption/Ionization Imaging Mass Spectrometry (MALDI-IMS) in the Development of Novel Small Molecule Drugs / Jihai Pang and Timothy L. Madden -- A Planar Integrated Micro-mass Spectrometer / Jörg Müller, Grigoriy Quiring, Maria Reinhardt-Szyba, Régulo Miguel Ramírez Wong and Henning Wehrs
Summary Annotation This text covers the various methods of validation for high performance liquid chromatography - mass spectrometry (LC-MS) analytical techniques and their applications in the analysis of a broad range of drugs in modern clinical pharmacology
Analysis Chemistry
Analytical biochemistry
Mass spectrometry
Analytical Chemistry
Bibliography Includes bibliographical references and index
Subject Drugs -- Analysis.
Liquid chromatography.
Mass spectrometry.
Pharmaceutical Preparations -- analysis
Chromatography, Liquid -- methods
Tandem Mass Spectrometry -- methods
Chromatography, Liquid
Mass Spectrometry
liquid chromatography.
mass spectrometry.
MEDICAL -- Drug Guides.
MEDICAL -- Nursing -- Pharmacology.
MEDICAL -- Pharmacology.
MEDICAL -- Pharmacy.
Science des matériaux.
Drugs -- Analysis
Liquid chromatography
Mass spectrometry
Form Electronic book
Author Xu, Quanyun A., 1961-
Madden, Timothy L.
ISBN 9781461438281