| Description |
1 online resource (xxv, 404 pages) : illustrations |
| Contents |
Key and criteria to the selection of an expression platform / Gerd Gellissen, Alexander W.M. Strasser, and Manfred Suckow -- Escherichia coli / Josef Altenbuchner and Ralf Mattes -- Pseudomonas fluorescens / Lawrence C. Chew [and others] -- Staphylococcus carnosus and other gram-positive bacteria / Roland Freudl -- Arxula adeninivorans / Erik Böer, Gerd Gellissen, and Gotthard Kunze -- Hansenula polymorpha / Hyun Ah Kang and Gerd Gellissen -- Pichia pastoris / Christine Ilgen, Joan Lin-Cereghino, and James M. Cregg -- Yarrowia lipolytica / Catherine Madzak, Jean-Marc Nicaud, and Claude Gaillardin -- Aspergillus sojae / Margreet Heerikhuisen, Cees van den Hondel, and Peter Punt -- Sordaria macrospora / Ulrich Kück and Stefanie Pöggeler -- Mammalian cells / Volker Sandig [and others] -- Plant cells / Rainer Fischer [and others] -- Wide-range integrative expression vectors for fungi, based on ribosomal DNA elements / Jens Klabunde [and others] -- Comparative fermentation / Stephan Hellwig [et al.] -- Recombinant hepatitis B vaccines : disease characterization and vaccine production / Pascale Brocke [et al.] -- Biopharmaceuticals and the industrial environment / Georg Melmer |
| Summary |
While the choices of microbial and eukaryotic expression systems for production of recombinant proteins are many, most researchers in academic and industrial settings do not have ready access to pertinent biological and technical information since it is normally scattered throughout the scientific literature. This book closes the gap by providing information on the general biology of the host organism, a description of the expression platform, a methodological section--with strains, genetic elements, vectors and special methods, where applicable--as well as examples of proteins produced with the |
| Analysis |
Biotechnology |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Recombinant Proteins -- biosynthesis.
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Bacteria.
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Eukaryotic Cells.
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Fungi.
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Technology, Pharmaceutical -- methods.
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Genetic vectors.
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Recombinant microorganisms.
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Recombinant proteins.
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| Form |
Electronic book
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| Author |
Gellissen, Gerd.
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John Wiley & Sons.
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| ISBN |
128051972X |
|
3527310363 (print. edition) |
|
3527603670 (electronic bk.) |
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3527604413 (electronic bk.) |
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9781280519727 |
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9783527310364 (print. edition) |
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9783527603671 (electronic bk.) |
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9783527604418 (electronic bk.) |
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