| Description |
1 online resource |
| Series |
Genetics - research and issues |
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Genetics--research and issues series.
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| Contents |
TELOMERES BIOLOGICAL FUNCTIONS, SEQUENCING AND AGING; TELOMERES BIOLOGICAL FUNCTIONS, SEQUENCING AND AGING; CONTENTS ; PREFACE; THE BIOLOGY OF TELOMERES IN MULTIPOTENTIAL STROMAL CELLS ; ABSTRACT ; INTRODUCTION ; Multipotential Stromal Cells ; Telomeres in Haematopoietic Stem Cells (HSCS) -- Gold Standard for MSC Research in this Area ; Aging and Telomere Shortening Following Standard in Vitro Expansion of BM MSCs ; The Relationship between Telomere Length in BM MSCs and Donor Age ; Improved Telomere Maintenance in BM MSCs Grown in Modified Culture Expansion Conditions |
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Telomere Dynamics in MSCs from Synovium and Periosteum Adipose-Derived MSCs ; Umbilical Cord-Derived MSCs ; Dental Pulp-Derived MSCs ; Human Skeletal Diseases Associated with Excessive or Accelerated Telomere Shortening ; Measurement of Telomeres in MSCs ; CONCLUSION ; REFERENCES ; TELOMERASE AND TELOMERE MAINTENANCE IN THE BLIGHT FUNGUS USTILAGO MAYDIS ; ABSTRACT ; INTRODUCTION ; THE U. MAYDIS CHROMOSOMAL ENDS ; THE TELOMERASE IN U. MAYDIS ; CHROMOSOME ENDS IN WILD U. MAYDIS ISOLATES AND LABORATORY STRAINS ; TELOMERE-LINKED HELICASES (TLH) IN FUNGI |
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DETECTION OF TLH TRANSCRIPTS IN U. MAYDIS CONCLUSION; REFERENCES ; TELOMERE LENGTH IN LYMPHOID MALIGNANCIES: A COMPARATIVE ANALYSIS ; ABSTRACT ; INTRODUCTION ; Telomeres; Lymphoid Malignancies ; Non-Hodgkin Lymphomas (NHL); Follicular Lymphoma (FL) ; Diffuse Large B-Cell Lymphoma (DLBCL) ; Mantle Cell Lymphoma (MCL) ; Plasma Cell Disorders ; Chronic Lymphocytic Leukemia (CLL) ; Telomeres in Lymphoid Malignancies ; MATERIALS AND METHODS; Patients ; Telomere Length Evaluation; RNA Extraction, Reverse Transcription and Real-Time Quantitative RT-PCR ; Cytogenetic Analysis |
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DNA Extraction and Nested PCR for BCL2/IGH@ Rearrangement Statistical Evaluation ; RESULTS ; TRF Lengths in B-Cell Malignancies ; Telomere Length and Genetic Characteristics ; Telomeric Protein Expression ; Comparison with the Literature ; DISCUSSION ; CONCLUSION ; ACKNOWLEDGMENTS ; REFERENCES ; AN OVERVIEW OF THE BIOLOGICAL FUNCTIONS OF TELOMERES ; ABSTRACT ; 1. INTRODUCTION ; 1.1. Telomeres: Definition and Structure ; 1.2. Telomere Functions: General Aspects ; 2. TELOMERE FUNCTIONS ; 2.1. The Main Function of Telomeres ; 2.1.1. Consequences of Telomere Loss |
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2.1.2. Consequences of Telomere Dysfunction 2.2. Telomeres Regulate the Replicative Life Span of Somatic Cells ; 2.3. Telomeres Contribute to Maintenance of Chromosome Topology in the Cell Nucleus; 2.4. Telomeres Play a Fundamental Role in the Proper Alignment of Chromosomes for Recombination during the First Meiotic Prophase and Assure Accurate Chromosome Segregation during Mitosis ; 2.5. The "Telomere Position Effect" ; 2.6. Several Telomere Functions Are Regulated by Helicases ; CONCLUSION ; REFERENCES ; HUMAN TELOMERES: STRUCTURE, FUNCTION AND TARGETING OF TELOMERE DNA/RNA ; ABSTRACT |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Description based on print version record |
| Subject |
Telomere.
|
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Telomerase.
|
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Gene mapping.
|
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Aging -- Molecular aspects.
|
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Telomere
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Telomerase
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Chromosome Mapping
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SCIENCE -- Life Sciences -- Molecular Biology.
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Telomerase
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Gene mapping
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Aging -- Molecular aspects
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Chromosomes
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Telomere
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| Form |
Electronic book
|
| Author |
Dominguez, Nicolás E
|
|
Pereyra, Sofia M
|
| LC no. |
2020676543 |
| ISBN |
9781619426375 |
|
1619426374 |
|
161942634X |
|
9781619426344 |
|
