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Title Origin and evolution of telomeres / [edited by] Jozef Nosek, Lubomír Tomáska
Published Austin, Tex. : Landes Bioscience, ©2008


Description 1 online resource (176 pages)
Series Molecular biology intelligence unit
Molecular biology intelligence unit.
Contents Telomerase : evolution, structure, and function / Marie-Eve Brault, Yasmin D'Souza, and Chantal Autexier -- Drosophila telomeres : a variation on the telomerase theme / Mary-Lou Pardue and P. Gregory DeBaryshe -- Alternative lengthening of telomeres in mammalian cells / Anthony J. Cesare and Roger R. Reddel -- T-loops, T-circles, and slippery forks / Sarah A. Compton [and others] -- Molecular diversity of telomeric sequences / Marita Cohn
Evolution of telomere binding proteins / Martin P. Horvath -- Telomeres : guardians of genomic integrity or double agents of evolution? / Michael J. McEachern -- Evolution, composition, and interrelated functions of telomeres and subtelomeres : lessons from plants / Jirí Fajkus [and others] -- Telomere position effect and the evolution of the genome / Frederique Magdinier, Alexandre Ottaviani, and Eric Gilson
Cancer as a microevolutionary process affecting telomere structure and dynamics : the contribution of telomeres to cancer / J. Arturo Londoño-Vallejo -- Prokaryotic telomeres : replication mechanisms and evolution / Sherwood R. Casjens and Wai Mun Huang -- Mitochondrial telomeres : an evolutionary paradigm for the emergence of telomeric structures and their replication strategies / Jozef Nosek and Lubomír Tomáska
Summary Linear chromosomes represent an evolutionary innovation associated with the origin of eukaryotic cells. This book describes how linear chromosomes and primordial pathways for maintaining their terminal structures, telomeres, emerged in early eukaryotes. Telomeres, derived from the Greek meaning terminal part, were first described by Hermann Muller in 1938. Telomeres are specialized structures that comprise the ends of linear chromosomes in eukaryotes. Linearity is crucial for chromosome pairing during meiosis and sexual reproduction. Inspired by Dobzhansky's dictum that "nothing in biology mak
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Telomere.
Molecular evolution.
Telomere -- physiology
Evolution, Molecular
Telomerase -- genetics
Telomerase -- physiology
Telomere -- genetics
SCIENCE -- Life Sciences -- Molecular Biology.
Molecular evolution
Form Electronic book
Author Nosek, Jozef, 1967-
Tomáska, Lubomír.
ISBN 9781435665040