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Title Temporomandibular joint and airway disorders : a translational perspective / G. Gary Demerjian, André Barkhordarian, Francesco Chiappelli, editors
Published Cham, Switzerland : Springer, 2018


Description 1 online resource (xv, 260 pages) : illustrations (some color)
Contents 880-01 Intro; Foreword; Preface; Acknowledgments; Introduction; Contents; Contributors; Part I: Translational Research; 1: Neuroanatomy of the Trigeminal Nerve and Proximal Innervation of the TMJ; 1.1 Introduction; 1.1.1 Neuroanatomy of the Temporomandibular Joint; Temporomandibular Joint and Trigeminal Nerve Connections; 1.1.2 Anatomy and Physiology of the Trigeminal Nerve and Its Central Connections; 1.1.3 Ophthalmic Nerve; 1.1.4 Maxillary Nerve; 1.1.5 Mandibular Nerve; 1.1.6 Otic Ganglion; Anterior Division of V3; Posterior Division of V3
880-01/(S 3.5 Neuroinflammation and Role of Neuropeptides3.6 Substance P; 3.7 VR1, VRL-1, and P2X3 Receptors in TMJ; 3.8 Calcitonin Gene-related Peptide (CGRP); 3.9 Peripheral Inflammation and CNS; 3.10 Microglia in CNS; 3.11 Turn-off Mechanisms of Macrophages; 3.12 Nucleotide Receptors P2X and P2Y; 3.13 P2X7, IL-1β, and Inflammasome; 3.14 ATP and Its Effects on Regulatory CD4 T Cells; References; 4: Lubricin: Toward a Molecular Mechanism for Temporomandibular Joint Disorders; 4.1 Molecular Characterization of Lubricin; 4.2 Experimental Model and Observations
1.1.7 Trigeminal Afferent Fibers1.1.8 Gasserian (Trigeminal, Semilunar) Ganglion; 1.1.9 Trigeminal Nerve Nuclei; Main Sensory Nucleus; Mesencephalic Nucleus; Spinal Trigeminal Nucleus; Trigeminal Motor Nucleus; 1.1.10 Spinal Trigeminal Nuclei Connections; 1.1.11 Reticular Formation; 1.1.12 Thalamus; 1.1.13 Auriculotemporal Nerve Connection to Systemic Neuropathology; References; 2: Neuroanatomy and Neurophysiology of the Trigeminal Network System; 2.1 Cranial Nerve Involvement in TMD; 2.2 The Somatosensory Receptors of the Human Oral Tissues
2.2.1 Mechanoreceptors2.2.2 Nociceptors; 2.2.3 Thermoreceptors; 2.3 Gasserian Ganglion; 2.4 Branches of Trigeminal Nerve; 2.4.1 Ophthalmic Nerve; 2.4.2 Maxillary Nerve; 2.4.3 Mandibular Nerve; Auriculotemporal (AT) Nerve; 2.5 Innervation of Cranial Dura Mater and Trigeminal Nerve; 2.6 Trigeminal Innervation of Major Intracranial Vessels; 2.7 Trigeminal Nerve (CN V) Pathways; 2.7.1 Motor Nucleus of the Trigeminal; 2.7.2 Sensory Nuclei; 2.7.3 Main Nucleus; 2.7.4 Mesencephalic; 2.7.5 Spinal Trigeminal Nucleus; 2.8 Trigeminal Nerve-Related Cranial Nerve Pathways
2.8.1 Facial Nerve2.8.2 Glossopharyngeal Nerve; 2.8.3 Vagus Nerve (CN X); 2.9 Neurophysiological Pathway Correspondence; 2.9.1 Trigeminofacial Reflex; 2.9.2 Trigeminocervical Reflex; 2.9.3 Trigeminocardiac Reflex; 2.9.4 Tonic Neck Reflex; References; 3: Neuroimmune and Systemic Manifestations of Neuroinflammation in the Temporomandibular Joint and Related Disorders; 3.1 Introduction; 3.2 Research and Findings; 3.3 Immune Surveillance and Signaling, Tissue Reaction, and Inflammation; 3.4 Blood-Brain Barrier (BBB) Disruption and Inflammation
Summary This book on the local and systemic manifestations and correlates of temporomandibular joint disorders (TMDs) encompasses the two intertwined facets of translational science - translational research and translational effectiveness - as they relate specifically to TMDs. The first part of the book, on recent translational research, focuses on topics such as the neuroanatomy and neurophysiology of the trigeminal nerve and trigeminal network system, the manifestations of neuroinflammation in TMDs, and the molecular mechanisms underlying TMDs. The second part discusses the clinical effectiveness of treatment approaches from the perspective of evidence-based dentistry, with careful attention to the critical relationships between dental malocclusions, the signs and symptoms of TMDs, and airway/breathing disorders. Interventions to correct for malocclusal conditions that lead to TMDs are examined, with explanation of the ways in which they can ameliorate a variety of local and systemic symptoms. This will be an excellent reference book for established practitioners, residents, interns, and students as well as a powerful cutting-edge document for researchers in the field
Notes Includes index
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (SpringerLink, viewed November 14, 2018)
In Springer eBooks
Subject Temporomandibular joint -- Diseases.
Temporomandibular Joint Disorders
Temporomandibular Joint Disorders -- complications
Oral & maxillofacial surgery.
Neurology & clinical neurophysiology.
MEDICAL -- Surgery -- General.
Temporomandibular joint -- Diseases
Form Electronic book
Author Demerjian, G. Gary, editor
Barkhordarian, André, editor
Chiappelli, Francesco, editor.
ISBN 9783319763675