| Description |
1 online resource |
| Contents |
Preface -- Contents -- Contributors -- Part I -- 1: Graft and Patient Survival -- Introduction -- Patient Survival -- Graft Survival -- Causes of Graft Loss: Major Etiologies -- Death with a Functioning Allograft -- Interstitial Fibrosis and Tubular Atrophy -- Glomerular Disease -- Risk Factors for Patient and Graft Survival -- Pretransplant Factors -- Waiting Time/Preemptive Transplantation -- HLA Matching -- Donor Source -- Donor Age -- Non-heart-Beating Donors -- Marginal Donors -- Dual Kidney Transplantation |
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Recipient Sensitization Posttransplant Factors -- Acute Rejection -- Delayed Graft Function -- Recipient Age -- Recipient Size -- Renal Function -- Recipient Race -- Hypertension -- Immunosuppressive Therapy -- Summary -- References -- 2: Immunological Assessment of the  Transplant Patient -- Introduction -- Barriers to Successful Transplantation -- ABO Incompatibility -- Major Histocompatibility Complex -- Preformed Anti-HLA Antibodies -- Influence of Mismatched HLA Antigens on Transplant Outcomes |
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Pretransplant Assessment of Anti-HLA Antibody Status The Pretransplant Crossmatch -- Standard Complement-Dependent Cytotoxicity or NIH Crossmatch -- Anti-human Globulin-Enhanced Crossmatch -- B Cell Cytotoxic Crossmatch -- Flow Crossmatch Test -- IgM Antibodies and Autoantibodies -- The Virtual Crossmatch -- Donor-Specific Antibodies -- Conclusions -- References -- 3: Recipient Evaluation -- The Decision Between Transplantation and Dialysis: Risks and Benefits -- The Medical Evaluation -- Cardiovascular Disease -- Infections -- Malignancies |
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Recurrent Disease in the Graft Additional Medical Considerations -- Psychosocial Evaluation -- Kidney Sources -- Timing of Transplant -- Conclusions -- References -- 4: Wait List Management -- Background -- The US Transplant System -- National Wait List -- Facts and Figures -- Wait Times -- Kidney Allocation -- Point System for Kidney Allocation -- Listing Practices -- Acceptance Criteria -- Lists Within the List -- ECD Listing Variability -- Sensitized Patients -- Timing of Transplantation |
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Preemptive Transplants (Just-in-Time Theory) Reevaluation -- Multiple Listing -- New Allocation System -- Principles of Inventory Management and Applications to the Wait List -- Summary -- References -- 5: Approach to the Highly Sensitized Patient -- Introduction -- Definition, Quantitation, and Monitoring of Sensitization -- Importance of Sensitization -- Causes of Sensitization -- Pathogenesis of Sensitization -- Immunobiology of Rejection in Sensitized Recipients -- Strategies to Optimize Outcomes in Sensitized Patients |
| Summary |
With the increased prevalence of kidney transplantation, transplant recipients are being treated in a variety of clinical settings - often beyond the transplant center. There is a greater need for clinicians and allied healthcare professionals to have appropriate guidance on managing these patients. Kidney Transplantation offers the latest evidence-based information on the full range of dilemmas in the medical management of kidney transplant recipients before, during and after transplantation. Beginning with the selection of patients who are candidates for transplantation, this authoritative guide covers the care of the patient on the waiting list and evaluation of donors, preoperative care, induction and immunosuppression maintenance. This wealth of new information and guidelines will serve as an important resource for the best possible care for transplant patients |
| Bibliography |
Includes bibliographical references |
| Notes |
Print version record |
| Subject |
Kidneys -- Transplantation -- Patients -- Medical care
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Kidneys -- Diseases -- Treatment
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Kidney Transplantation -- methods
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MEDICAL -- Surgery -- General.
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Médecine.
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Kidneys -- Diseases -- Treatment
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| Form |
Electronic book
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| Author |
Weir, Matthew R., 1952- editor.
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Lerma, Edgar V., editor
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| ISBN |
9781493903429 |
|
149390342X |
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9781493903436 |
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1493903438 |
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9781493942725 |
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1493942727 |
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