Title Biomarkers in cancer detection and monitoring of therapeutics. Volume 2, Diagnostic and therapeutic applications / edited by Ranbir Chander Sobti, Masatoshi Watanabe, Aastha Sobti

Published London : Academic Press, [2024]

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Description 1 online resource Contents Intro -- Biomarkers in Cancer Detection and Monitoring of Therapeutics: Volume 2: Diagnostic and Therapeutic Applications -- Copyright -- Contents -- Contributors -- Preface -- Chapter One: Oral squamous cell carcinoma -- 1. Oral cancer -- 2. Oral squamous cell carcinoma -- 3. Epidemiology -- 4. Etiology -- Impact of tobacco products -- Patterns and trends in tobacco use -- Use of smokeless tobacco products -- 5. Precursor lesions -- 5.1. Genetically acquired potentially malignant disorders -- 5.2. Tobacco-induced potentially malignant disorders 5.3. Immune-mediated potentially malignant disorders -- 5.4. Genetically inherited potentially malignant disorders -- 6. Oral epithelial dysplasia -- 7. Pathogenesis -- 7.1. Autophagy -- 8. Cancer stem cells -- 9. Tumor microenvironment -- 10. Epithelial-mesenchymal transition -- 11. Metastasis -- 12. Oral bacteria in oral carcinogenesis -- 13. Clinical features -- Salient features specific to subsite -- 14. Diagnosis -- 14.1. Adjunctive aids for early detection -- Nano-diagnostics -- Lab-on-chip/microfluidics -- Liquid biopsy -- Microarray technology -- Next generation sequencing -- Omics Genomics -- Transcriptomics -- Proteomics -- Metabolomics -- Staging of oral squamous cell carcinoma -- 15. Histopathological features -- 16. Treatment -- 16.1. Surgical resection -- Management of primary lesion -- Management of neck nodes -- 16.2. Chemotherapy -- Adjuvant chemotherapy -- Adjuvant chemoradiotherapy -- Primary chemoradiation -- Induction chemotherapy -- In the management of metastatic disease -- 16.3. Nanotechnology in carcinoma therapy -- Chemoprevention using nanoparticles -- 16.4. Radiotherapy -- 16.5. Immunotherapy -- Cytokines -- Toll-like receptors Immune checkpoint inhibitors -- Immune checkpoint activators -- 16.6. Therapeutic markers -- 17. Prognosis -- 17.1. Clinical factors -- 17.2. Histopathological factors -- 17.3. Metastasis -- References -- Chapter Two: Genetic predisposition and pathophysiology of oral squamous cell carcinoma -- 1. Introduction -- 1.1. Microbial flora -- 1.2. Oral microbial flora -- 1.3. Oral microbial flora and cancer -- 1.4. Squamous cell carcinoma of the head and neck -- 2. Oral squamous cell carcinoma and glucose transporters -- 2.1. Human glucose transporters 2.2. Glucose transporters (GLUT 1) and its expression -- 3. Oral squamous cell carcinoma and methylated genes -- 3.1. Variation of methylated genes in cancer conditions -- 3.2. DNA methylation modifications and its implications -- References -- Chapter Three: Molecular biomarkers in gastric cancer -- 1. Introduction -- 2. RNF43 -- 3. APC -- 4. ARID1A -- 5. ARID2 -- 6. MSI -- 7. MALTA1-GLT1 fusion -- 8. TP53 -- 9. RB1 -- 10. ERBB2 -- 11. C-MET -- 12. EGFR -- 13. PD-L1 -- 14. Epstein-Barr virus -- 15. VEGF-A -- 16. CD44 -- 17. E-cadherin -- 18. Matrix metalloproteinases (MMPs) -- 19. Conclusions Notes Print version record Subject Tumor markers -- Diagnostic use. Tumor markers -- Therapeutic use Tumor markers -- Diagnostic use Form Electronic book Author Sobti, Ranbir Chander Watanabe, Masatoshi Sobti, Aastha ISBN 9780323951159 0323951155

Other Titles Diagnostic and therapeutic applications

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