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Tumor markers -- Congresses : Developing biomarker-based tools for cancer screening, diagnosis, and treatment : the state of the science, evaluation, implementation, and economics : workshop summary / Margie Patlak and Sharyl Nass, rapporteurs ; National Cancer Policy Forum  2006 1
Tumor markers -- Diagnostic use.   8
Tumor markers -- Laboratory manuals : Lung cancer. Volume 2, Diagnostic and therapeutic methods and reviews / edited by Barbara Driscoll  2003 1
Tumor markers -- Periodicals   2
Tumor markers -- Research : Murine models, energy balance, and cancer / Nathan A. Berger, editor  2015 1
Tumor markers -- Research -- Methodology : Ovarian cancer : methods and protocols / edited by John M.S. Bartlett  2001 1
Tumor markers -- Therapeutic use   3
 

Tumor, Merkel Cell -- See Carcinoma, Merkel Cell


A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245)
  1
 

Tumor Metabolite Marker -- See Biomarkers, Tumor


Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or BODY FLUIDS. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including HORMONES; ANTIGENS; amino and NUCLEIC ACIDS; ENZYMES; POLYAMINES; and specific CELL MEMBRANE PROTEINS and LIPIDS
  1
 

Tumor Metabolite Markers -- See Biomarkers, Tumor


Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or BODY FLUIDS. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including HORMONES; ANTIGENS; amino and NUCLEIC ACIDS; ENZYMES; POLYAMINES; and specific CELL MEMBRANE PROTEINS and LIPIDS
  1
 

Tumor metastasis -- See Metastasis


Here are entered works on the transfer of cancer to an organ or part of the body remote from the primary site. Works on the ability of cancer to infiltrate and actively destroy surrounding tissue are entered under Cancer invasiveness
  1
Tumor Microenvironment   26
Tumor Microenvironment -- genetics : The tumor microenvironment : methods and protocols / edited by Josie Ursini-Siegel, Nicole Beauchemin  2016 1
Tumor Microenvironment -- immunology : Tumor microenvironment / Peter P. Lee, Francesco M. Marincola, editors  2020 1
Tumor Microenvironment -- physiology : Tumor microenvironment and cellular stress : signaling, metabolism, imaging, and therapeutic targets / Constantinos Koumenis, Ester Hammond, Amato Giaccia, editors  2014 1
 

Tumor Microenvironments -- See Tumor Microenvironment


The milieu surrounding neoplasms consisting of cells, vessels, soluble factors, and molecules, that can influence and be influenced by, the neoplasm's growth
  1
 

Tumor, Myocardial (Rhabdomyomas and Fibromas) -- See Heart Neoplasms


Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM
  1
 

Tumor Necrosis Factor -- See Tumor Necrosis Factor-alpha


Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS
  1
Tumor necrosis factor.   8
Tumor necrosis factor -- Agonists -- Therapeutic use : Therapeutic targets of the TNF superfamily / edited by Iqbal S. Grewal  2009 1
Tumor Necrosis Factor-alpha : Tumor necrosis factor : methods and protocols / edited by Angelo Corti and Pietro Ghezzi  2004 1
Tumor Necrosis Factor-alpha -- antagonists & inhibitors : TNF-alpha inhibitors / edited by J.M. Weinberg and R. Buchholz  2006 1
Tumor Necrosis Factor-alpha -- therapeutic use : The handbook of biological therapy : a guide to the use and safety of biological therapies in rheumatology, dermatology, and gastroenterology / Bruce Kirkham [and others]  2008 1
Tumor necrosis factor -- Congresses : Advances in TNF family research : proceedings of the 12th International TNF Conference, 2009 / David Wallach, Andrew Kovalenko, Marc Feldmann, editors  2011 1
Tumor necrosis factor -- Inhibitors   4
Tumor necrosis factor -- Laboratory manuals   2
 

Tumor Necrosis Factor Ligand Superfamily Member 2 -- See Tumor Necrosis Factor-alpha


Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS
  1
Tumor necrosis factor -- Pathophysiology : TNF pathophysiology : molecular and cellular mechanisms / volume editors, G. Kollias, P.P. Sfikakis  2010 1
Tumor necrosis factor -- Physiological effect : Death receptors and cognate ligands in cancer / Holger Kalthoff, ed  2009 1
 

Tumor Necrosis Factor Receptor -- See Receptors, Tumor Necrosis Factor


Cell surface receptors that bind TUMOR NECROSIS FACTORS and trigger changes which influence the behavior of cells
  1
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins -- physiology : TNF receptor associated factors (TRAFs) / edited by Hao Wu  2007 1
 

Tumor Necrosis Factor Receptor Superfamily, Member 6 -- See fas Receptor


A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome
  1
Tumor Necrosis Factor Receptor Superfamily, Member 9 -- immunology : CD137 pathway : immunology and diseases / edited by Lieping Chen  2006 1
 

Tumor Necrosis Factor Receptor Superfamily, Member 10 -- See Receptors, TNF-Related Apoptosis-Inducing Ligand


Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved DEATH DOMAINS that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM
  1
 

Tumor Necrosis Factor Receptor Superfamily, Member 10a -- See Receptors, TNF-Related Apoptosis-Inducing Ligand


Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved DEATH DOMAINS that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM
  1
 

Tumor Necrosis Factor Receptor Superfamily, Member 10b -- See Receptors, TNF-Related Apoptosis-Inducing Ligand


Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved DEATH DOMAINS that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM
  1
 

Tumor Necrosis Factor Receptors -- See Receptors, Tumor Necrosis Factor


Cell surface receptors that bind TUMOR NECROSIS FACTORS and trigger changes which influence the behavior of cells
  1
Tumor necrosis factor -- Receptors.   5
Tumor necrosis factor -- Receptors -- Physiological effect : Death receptors and cognate ligands in cancer / Holger Kalthoff, ed  2009 1
 

Tumor Necrosis Factor Superfamily Ligands -- See Tumor Necrosis Factors


A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated through TUMOR NECROSIS FACTOR RECEPTORS which induce APOPTOSIS
  1
Tumor necrosis factor -- Therapeutic use : Tumor necrosis factor / Toma P. Rossard, editor  2009 1
Tumor Necrosis Factors   3
Tumor Necrosis Factors -- genetics : Tumor necrosis factor / Toma P. Rossard, editor  2009 1
Tumor Necrosis Factors -- immunology : TNF pathophysiology : molecular and cellular mechanisms / volume editors, G. Kollias, P.P. Sfikakis  2010 1
Tumor Necrosis Factors -- metabolism   2
Tumor Necrosis Factors -- physiology   3
Tumor Necrosis Factors -- therapeutic use : Therapeutic targets of the TNF superfamily / edited by Iqbal S. Grewal  2009 1
Tumor-Nekrose-Faktor : Death receptors and cognate ligands in cancer / Holger Kalthoff, ed  2009 1
 

Tumor, Nervous System -- See Nervous System Neoplasms


Benign and malignant neoplastic processes arising from or involving components of the central, peripheral, and autonomic nervous systems, cranial nerves, and meninges. Included in this category are primary and metastatic nervous system neoplasms
  1
 

Tumor, Neuroendocrine -- See Neuroendocrine Tumors


Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition
  1
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