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Title The ubiquitin-proteasome proteolytic system : from classical biochemistry to human diseases / editors, Aaron J. Ciechanover, Maria G. Masucci
Published New Jersey : World Scientific, ©2002

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Description 1 online resource (xx, 220 pages) : illustrations (some color)
Series Recent advances in human biology ; v. 9
Recent advances in human biology ; v. 9.
Contents The ubiquitin system and some of its roles in cell cycle control / A. Hershko -- The ubiquitin system and the N-end rule pathway / A. Varshavsky -- Phosphorylation-dependent substrate recognition in ubiquitin-mediated proteolysis / M. Tyers, P. Klein and T. Pawson -- The 26S proteasome: a supramolecular assembly designed for controlled proteolysis / W. Baumeister and P. Zwickl -- Mechanisms and regulation of ubiquitin-mediated, limited processing of the NF-[symbol] precursor protein p105 / A. Ciechanover [and others] -- Regulation of receptor tyrosine kinases by ubiquitination / A. Citri and Y. Yarden -- Regulation of p27 degradation / J. Bloom and M. Pagano -- Ubiquitin system-dependent regulation of growth hormone receptor signal transduction and effects of oxidative stress / C.M. Alves dos Santos and G.J. Strous -- Inhibition of the ubiquitin-proteasome system by a viral repetitive sequence / N.P. Dantuma and M.G. Masucci -- Autosomal recessive juvenile Parkinsonism and the ubiquitin pathway / K. Tanaka [and others]
Summary Annotation Ubiquitin-proteosome-dependent proteolysis is central to an incredible multitude of processes in all eukaryotes, including the cell cycle, cell growth and differentiation, embryogenesis, apoptosis, signal transduction, DNA repair, regulation of transcription and DNA replication, transmembrane transport, endocytosis, stress responses, antigen presentation and other aspects of the immune response, the functions of the nervous system including circadian rhythms, axon guidance and acquisition of memory
Bibliography Includes bibliographical references
Notes Print version record
Subject Ubiquitin.
Proteolytic enzymes.
Proteins -- Metabolism.
Ubiquitins
Peptide Hydrolases
MEDICAL -- Biochemistry.
Proteins -- Metabolism
Proteolytic enzymes
Ubiquitin
Form Electronic book
Author Ciechanover, Aaron J.
Masucci, Maria G.
LC no. 2003271197
ISBN 9789812776877
9812776877
9789812381002
9812381007