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Book Cover

Title VEGF in development / [edited by] Christiana Ruhrberg
Published Austin, Tex. : Landes Bioscience/ ; New York : Springer Science+Business Media, ©2008


Description 1 online resource (106 pages) : illustrations (some color)
Series Molecular biology intelligence unit
Molecular biology intelligence unit (Unnumbered)
Contents The biology of vascular endothelial cell growth factor isoforms / Yin-Shan Ng -- VEGF receptor signalling in vertebrate development / Joaquim Miguel Vieira, Christiana Ruhrberg, and Quenten Schwarz -- VEGF gene regulation / Marcus Fruttiger -- Embryonic vasculogenesis and hematopoietic specification / Lauren C. Goldie, Melissa K. Nix, and Karen K. Hirschi -- Role of VEGF in organogenesis / Jody J. Haigh -- VEGF and endothelial guidance in angiogenic sprouting / Holger Gerhardt -- Vascular and nonvascular roles of VEGF in bone development / Christa Maes and Geert Carmeliet -- VEGF in the nervous system / Jeffrey M. Rosenstein, Janette M. Krum, and Christiana Ruhrberg
Summary This book is devoted to vascular endothelial growth factor A (VEGF or VEGFA), a secreted signalling protein of great significance for development and disease in vertebrates. VEGFA controls the proliferation, migration, specialisation and survival of vascular endothelial cells, and it is therefore essential for the establishment of a functional blood vessel circuit. In addition, VEGFA is emerging as a versatile patterning factor for several non-endothelial cell types in vertebrates. Thus, it plays a central role during organ development at multiple levels, including blood vessel growth, vessel-
Analysis biochemie
life sciences
Biology (General)
Biologie (algemeen)
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Neovascularization.
Vascular endothelial growth factors.
Life sciences.
Physical sciences.
Biological products.
Vascular Endothelial Growth Factor A
Growth and Development
Biological Science Disciplines
Physiological Phenomena
Vascular Endothelial Growth Factors
Angiogenic Proteins
Natural Science Disciplines
Intercellular Signaling Peptides and Proteins
Phenomena and Processes
Disciplines and Occupations
Biological Factors
Amino Acids, Peptides, and Proteins
Vascular Endothelial Growth Factor A -- physiology
Chemicals and Drugs
Growth and Development -- physiology
Neovascularization, Pathologic
biological sciences.
physical sciences.
MEDICAL -- Physiology.
SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
Vascular Endothelial Growth Factor A -- physiology.
Growth and Development -- physiology.
Vascular Endothelial Growth Factors.
Sciences de la vie.
Physical sciences
Life sciences
Vascular endothelial growth factors
Form Electronic book
Author Ruhrberg, Christiana
LC no. 2008009257
ISBN 9780387786322