Vasoconstrictor Factors, Endothelium-Derived -- See Endothelins
21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three members, ENDOTHELIN-1; ENDOTHELIN-2; and ENDOTHELIN-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP
Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
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Vasomotor Center(VMC) : Schaum's Feedback and Control Systems Problem 7.29: Transfer Function Example 2 / Carlotta A. Berry
Vasomotor conditioning -- Computer simulation. : Utilization of computer modeling in the prescription of selected aerobic conditioning programs : a systems approach / by Frederick Reginald Loveys
Vason, George, 1771 or 2-1838 : Narrative of the late George Vason of Nottingham : one of the first missionaries sent out by the London Missionary Society in the ship Duff, Captain Wilson, 1796 : giving an account of his voyage outward, settlement in Tongataboo, apostacy, heathen life, escape from the island, return to England, subsequent life, and death in 1838, aged 66 years ; with a preliminary essay on the geography of the South Sea Islands, also a description of the manners, habits, customs, traditions, &c. &c. of the inhabitants, and a succinct account of the South Sea Island Mission / by James Orange