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Title Ototoxicity / [edited by] Peter S. Roland, John A. Rutka
Published Hamilton, Ont. ; Lewiston, NY : BC Decker, 2004


Description 1 online resource (xii, 220 pages) : illustrations
Series Book cum disc
Book cum disk
Contents 1. Anatomy and physiology of the cochlea / Karen S. Pawlowski -- 2. Physiology of the vestibular system / John A. Rutka -- 3. Salicylates, nonsteroidal anti-inflammatory drugs, quinine, and heavy metals / Narayanan Prepageran and John A. Rutka -- 4. Ototoxicity of loop diuretics / Narayanan Prepageran, Andrew R. Scott and John A. Rutka -- 5. Cinical uses of Cisplatin / Jeremy Sturgeon -- 6. Ototoxicity of platinum compounds / Michael Anne Gratton and Brendan J. Smyth -- 7. Iron chelating and other chemotherapeutic agents : the vinca alkaloids / Andrew R. Scott, Narayanan Prepageran and John A. Rutka -- 8. Clinical aminoglycoside ototoxicity / Coleman Rotstein and Lionel A. Mandell -- 9. Mechanisms for aminoglycoside ototoxicity : basic science research / Jochen Schacht -- 10. Macrolides / Andrew R. Scott and John A. Rutka -- 11. Middle ear effects of ototopical agents / Charles G. Wright and Peter S. Roland -- 12. Topical aminoglycoside cochlear toxicity / Peter S. Roland and Charles G. Wright -- 13. Topical aminoglycoside vestibular toxicity / Narayanan Prepageran, Vitaly E. Kisilevsky and John A. Rutka -- 14. Chloramphenicol, colymycin, and polymyxin / Leonard P. Rybak and Srinivasan Krishna -- 15. Topical antifungals / Lawrence W.C. Tom, Lisa M. Elden and Roger R. Marsh -- 16. Surgical disinfectants and antiseptics / Andrew R. Scott, Narayanan Prepageran and John A. Rutka -- 17. Genetic factors in aminoglycoside ototoxicity / Nathan Fischel-Ghodsian -- 18. Audiologic monitoring for ototoxicity / Kathleen C.M. Campbell -- 19. Monitoring vestibular ototoxicity / Vitaly E. Kisilevsky, R. David Tomlinson, Paul Ranalli and Narayanan Prepageran -- 20. Ototoxic damage to hearing : otoprotective therapies / Thomas R. Van De Water and Leonard P. Rybak -- 21. Systemic treatment of bilateral Meniere's disease / Sumit K. Agrawal and Lorne S. Parnes -- 22. Intratympanic gentamicin in the treatment of Meniere's disease / Brian W. Blakley -- 23. Medicolegal aspects of ototoxicity / Peter E. Rhatican, Sloan H. Mandel and John A. Rutka -- App. 1. Information provided to lawyers -- App. 2. Summary of the 2004 AAO-HNS consensus panel recommendations -- App. 3. Major groups of agents recognized to be ototoxic in humans
Summary "This original text on ototoxicity belongs in the hands of every doctor who prescribes certain systemic or topical drugs - such as the aminoglycosides - and everyone who sees patients with ear disorders." "Written by experts in the field, the text reviews all classes of medication known to cause functional impairment and cellular damage to the tissues of the middle ear - especially the end organs of the cochlear and vestibular divisions of the eight cranial nerves. The text opens with basic anatomy and physiology and continues with clinical manifestations of ototoxicity, pathophysiology, prevention, and treatment, and medical-legal issues for each class of compounds. Case presentations, followed by discussion, illustrate key medicolegal concepts."--Jacket
Bibliography Includes bibliographical references and index
Notes Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. MiAaHDL
digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL
Print version record
committed to retain 20170930 20421231 HathiTrust{HathiTrust Shared Print commitment 2017} AEU
Subject Middle ear -- Effect of drugs on
Cochlea -- Effect of drugs on
Vestibular apparatus -- Effect of drugs on
Aminoglycosides -- Toxicology
Ear -- Diseases -- Chemotherapy
Cochlea -- drug effects
Ear, Middle -- drug effects
Aminoglycosides -- toxicity
Ear Diseases -- drug therapy
Hearing Disorders -- chemically induced
Vestibular Nerve -- drug effects
Aminoglycosides -- Toxicology.
Vestibular apparatus -- Effect of drugs on.
Form Electronic book
Author Roland, Peter S
Rutka, John A