| Description |
1 online resource (136 pages) |
| Contents |
""Xenotransplantation""; ""Copyright""; ""Contents""; ""Executive Summary""; ""RECOMMENDATION 1""; ""RECOMMENDATION 2""; ""RECOMMENDATION 3""; ""RECOMMENDATION 4""; ""RECOMMENDATION 5""; ""A NECESSARY CAVEAT""; ""1 Setting the Stage""; ""INTRODUCTION""; ""STUDY PROCESS AND REPORT ORGANIZATION""; ""APPROACHING QUESTIONS OF OPPORTUNITIES AND RISKS""; ""The Potential Benefits of Xenotransplantation""; ""Providing Adequate Organ Supply""; ""Providing Cells and Tissues to Treat Disease""; ""Risk: Precedent and Uncertainty""; ""2 Assessing the Science Base""; ""INTRODUCTION"" |
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""STAGES OF THE IMMUNE RESPONSE""""Progress in Molecular and Cellular Biology""; ""Mechanisms of Hyperacute Rejection""; ""Mechanisms of T-Cell-Mediated Rejection""; ""NOVEL THERAPEUTIC APPROACHES""; ""Limitations of Immunosuppression in Xenotransplantation""; ""Modification of the Source Animal""; ""Antibody Masking""; ""Transgenic Modification""; ""Gene Knockout""; ""Antisense RNA""; ""Modification of the Host""; ""Bone Marrow Chimerism""; ""Microchimerism""; ""Modification of the Graft: Encapsulation""; ""3 Infectious Disease Risk to Public Health Posed by Xenografting"" |
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""ANIMAL INFECTIONS AND XENOTRANSPLANTATION""""BASIS FOR PUBLIC HEALTH CONCERN""; ""METHODS OF RISK EVALUATION""; ""DETECTION METHODS""; ""NEED FOR A REGISTRY""; ""SUMMARY""; ""4 Ethics and Public Policy""; ""PATIENTS, ETHICS, AND SOCIETY""; ""Patients' Perspectives""; ""Informed Consent""; ""Justice and Fairness Issues: Organ Allocation and Research""; ""Social Acceptance of Xenotransplants""; ""Social Acceptance of Infectious Disease Risk""; ""VALUE AND USE OF ANIMALS""; ""Ethical Theory""; ""History of Social Responses to Xenotransplantation"" |
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""A Moderate Ethical Perspective of Xenotransplantation""""Application to Xenotransplantation""; ""ECONOMIC ISSUES REGARDING XENOTRANSPLANTS""; ""Aggregate Expenditures for Organ Transplantation""; ""Transplant Procedure Expenses""; ""Ethics and Public Policy""; ""Expenditures for Xenotransplantation""; ""Insurance Coverage""; ""Impact of Managed Care""; ""Justice, Fairness, and the Ability to Pay""; ""REVIEWING AND MONITORING XENOTRANSPLANTATION""; ""FDA Regulation of Xenotransplantation""; ""Current Regulatory Framework""; ""5 Conclusions and Recommendations""; ""References"" |
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""A Workshop Agenda""""XENOGRAFT TRANSPLANTATION: SCIENCE, ETHICS, AND PUBLIC POLICY""; ""SPEAKERS AND PANELISTS""; ""B List of Participants""; ""WORKSHOP ON XENOGRAFT TRANSPLANTATION: SCIENCE, ETHICS, AND PUBLIC POLICY""; ""C Immunosuppression in Allotransplantation"" |
| Notes |
Print version record |
| Subject |
Xenografts -- Government policy -- United States
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Xenografts -- Moral and ethical aspects
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United States.
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| Form |
Electronic book
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| ISBN |
9780309589567 |
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0309589568 |
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