| Description |
1 online resource (xxvii, 166 pages) : illustrations (some color) |
| Series |
Advances in experimental medicine and biology ; v. 637 |
|
Advances in experimental medicine and biology ; v. 637.
|
| Contents |
Historical aspects of xeroderma pigmentosum and nucleotide excision repair / James E. Cleaver -- Clinical features of xeroderma pigmentosum / Ulrich R. Hengge and Steffen Emmert -- Xeroderma pigmentosum and skin cancer / Leela Daya-Grosjean -- XPA gene, its product and biological roles / Ulrike Camenisch and Hanspeter Nogeli -- XPB and XPD between transcription and DNA repair / Brian D. Beck, Dae-Sik Hah, and Suk-Hee Lee -- XPC: its product and biological roles / Kaoru Sugasawa -- The XPE gene of xeroderma pigmentosum : its product and biological roles / Drew Bennett and Toshiki Itoh -- XPF/ERCC4 and ERCC1 : their products and biological roles / Lisa D. McDaniel and Roger A. Schultz -- XPG: its products and biological roles / Orlando D. Schorer -- Xeroderma pigmentosum variant, XPV: its product and biological roles / Chikahide Masutani, Fumio Hanaoka, and Shamim I. Ahmad |
|
Other proteins interacting with XP proteins / Steven M. Shell and Yue Zou -- The nucleotide excision repair of DNA in human cells and its association with xeroderma pigmentosum / Alexei Gratchev -- Roles of oxidative stress in xeroderma pigmentosum / Masaharu Hayashi -- Xeroderma pigmentosum : its overlap with trichothiodystrophy, Cockayne syndrome, and other progeroid syndromes / W. Clark Lambert, Claude E. Gagna, and Muriel W. Lambert -- Population distribution of xeroderma pigmentosum / Abdul Manan Bhutto and Sandra H. Kirk -- Progress and prospects of xeroderma pigmentosum therapy / Alain Sarasin -- Animal models of xeroderma pigmentosum / Xue-Zhi Sun [and others] |
| Summary |
To understand the molecular mechanisms of XP, XP mouse models have been used, and mice deficient in XPA, XPC, XPD, XPG, XPF, and XPA/CSB have been produced and analysed. This title includes a chapter that analyzes the world distribution of XP and shows that Japan has the highest incidence of XP and of varying complementation groups |
| Analysis |
geneeskunde |
|
medicine |
|
biomedische wetenschappen |
|
biomedicine |
|
Medicine (General) |
|
Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Xeroderma pigmentosum -- Molecular aspects
|
|
DNA repair.
|
|
Xeroderma Pigmentosum -- genetics
|
|
DNA Repair
|
|
DNA Repair Enzymes -- genetics
|
|
DNA Repair-Deficiency Disorders -- genetics
|
|
Xeroderma Pigmentosum -- therapy
|
|
MEDICAL -- Dermatology.
|
|
Xeroderma pigmentosum -- Molecular aspects.
|
|
DNA repair.
|
|
Xeroderma Pigmentosum -- genetics.
|
|
DNA Repair Enzymes -- genetics.
|
|
DNA Repair-Deficiency Disorders -- genetics.
|
|
Xeroderma Pigmentosum -- therapy.
|
|
Sciences de la vie.
|
|
Biomédecine.
|
|
DNA repair
|
| Form |
Electronic book
|
| Author |
Ahmad, Shamim I.
|
|
Hanaoka, Fumio, 1946-
|
| ISBN |
9780387095998 |
|
0387095993 |
|
