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Title Vascular mechanisms in CNS trauma / Eng H. Lo, Josephine Lok, MingMing Ning, Michael J. Whalen, editors
Published New York, NY : Springer, 2014


Description 1 online resource (xx, 518 pages) : illustrations (some color)
Series Springer Series in Translational Stroke Research
Springer series in translational stroke research.
Contents Molecular Mechanisms -- CNS Barriers in Neurotrauma / Adam Chodobski, Brian J. Zink and Joanna Szmydynger-Chodobska -- Mechanisms of Cerebral Edema Leading to Early Seizures After Traumatic Brain Injury / Philip H. Iffland II, Gerald A. Grant and Damir Janigro -- Human Cerebral Blood Flow and Traumatic Brain Injury / David A. Hovda and Thomas C. Glenn -- Gliovascular Targets in Traumatic CNS Injury / Arjun Khanna, Brian P. Walcott, Kristopher T. Kahle, Volodymyr Gerzanich and I. Marc Simard -- Neurovascular Responses to Traumatic Brain Injury / Josephine Lok, Ken Arai, Shu-zhen Guo, Wendy Leung, Takakuni Maki, Deepti Navaratna [and 5 others] -- The Effects of Intravascular Coagulation and Microthrombosis on Cerebral Perfusion After Brain Trauma / Monisha A. Kumar, Douglas H. Smith and Sherman C. Stein -- Barriers to Drug Delivery for Brain Trauma / F. Anthony Willyerd, Philip E. Empey, Patrick M. Kochanek and Robert S.B. Clark -- Angiogenesis and Functional Recovery After Traumatic Brain Injury / Yanlu Zhang, Ye Xiong, Asim Mahmood, Zheng Gang Zhang and Michael Chopp -- Vascular Mechanisms in Spinal Cord Injury / Theo Hagg -- Neurovascular Mechanisms of Ischemia Tolerance Against Brain Injury / Kunjan R. Dave, John W. Thompson, Jake T. Neumann, Miguel A. Perez-Pinzon and Hung W. Lin -- Stem Cells for Neurovascular Repair in CNS Trauma / Mibel M. Pabón, Travis Dailey, Naoki Tajiri, Kazutaka Shinozuka, Hiroto Ishikawa [and 3 others] -- Vascular Actions of Hypothermia in Brain Trauma / W. Dalton Dietrich and Helen M. Bramlett -- Experimental Models and Methods -- Vascular Responses in Rodent Models of Traumatic Brain Injury / Xiaoshu Wang, Zhanyang Yu, Zhengbu Liao, Qi Liu, MingMing Ning, Xiaochuan Sun [and 3 others] -- SAH Models: Review, New Modification, and Prospective / Sheng Chen, Damon Klebe, Alexander Vakhmyanin, Mutsumi Fujii and John H. Zhang -- Age and Sex Differences in Hemodynamics in a Large Animal Model of Brain Trauma / William M. Armstead and Monica S. Vavilala -- Neutrophils as Determinants of Vascular Stability in the Injured Spinal Cord / Alpa Trivedi, Sang Mi Lee, Haoqian Zhang, Linda J. Noble-Haeusslein -- Blood Biomarkers for Acute CNS Insults: Traumatic Brain Injury and Stroke / Olena Glushakova, Stefania Mondello and Ronald L. Hayes -- Biomaterials for CNS Injury / Teck Chuan Lim and Myron Spector -- Isolated Blood Vessel Models for Studying Trauma / Eugene V. Golanov -- Clinical Challenges and Opportunities -- Managing Edema and Intracranial Pressure in the Intensive Care Unit / Brian M. Cummings, Phoebe H. Yager, Sarah A. Murphy, Brian Kalish, Chetan Bhupali [and 4 others] -- Surgical Management of Traumatic Brain Edema / Takeshi Maeda, Tatsuro Kawamata, Atsuo Yoshino and Yoichi Katayama -- Optimizing Hemodynamics in the Clinical Setting / Jose Alberto Toranzo and Claudia S. Robertson -- Cerebrovascular Autoregulation and Monitoring of Cerebrovascular Reactivity / Philip M. Lewis, Marek Czosnyka, Piotr Smielewski and John D. Pickard -- Cerebrovascular Responses After Pediatric Traumatic Brain Injury / Steven L. Shein, Nikki Miller Ferguson and Michael J. Bell -- Subdural Hematoma in Non-accidental Head Injury / Jennifer C. Munoz Pareja, Josephine Lok, Natan Noviski and Ann-Christine Duhaime -- Blood Genomics After Brain Ischemia, Hemorrhage, and Trauma / Da Zhi Liu, Glen C. Jickling, Boryana Stamova, Xinhua Zhan, Bradley P. Ander and Frank N. Sharp -- Molecular Biomarkers in Neurocritical Care: The Next Frontier / Sherry H.-Y. Chou, Eng H. Lo and MingMing Ning -- Bedside Monitoring of Vascular Mechanisms in CNS Trauma: The Use of Near-Infrared Spectroscopy (NIRS) and Transcranial Doppler (TCD) / Sarah A. Murphy, Brian M. Cummings, David A. Boas and Natan Noviski -- In Vivo MRI and MRS of Cerebrovascular Function Following Traumatic Brain Injury / Chandler Sours and Rao P. Gullapalli
Summary Vascular Mechanisms in CNS Trauma focuses on the vascular aspects of brain and spinal cord trauma. Twenty nine chapters are arranged in three sections:Molecular Mechanisms; Experimental Models and Methods; and Clinical Challenges and Opportunities. The first section addresses topics in the basic biology of brain and spinal cord trauma, ranging from the pathophysiology of cerebral endothelial cells and gliovascular interactions to the role of stem cells in neurovascular repair. The second section covers experimental methods in rodent and in large animal models of CNS injury, as well as the use of biomaterials and biomarkers in studying the mechanisms of tissue response. The third section deals with clinical issues in the monitoring and treatment of the patient with traumatic injury of the brain and spinal cord. Contributors to the book include an integrated mix of basic scientists and clinicians from diverse institutions. By presenting salient issues in CNS trauma from a vascular perspective, this book should make a unique contribution to the understanding of traumatic brain and spinal cord injury
Notes Online resource; title from PDF title page (SpringerLink, viewed November 11, 2013)
Subject Central nervous system -- Wounds and injuries.
Cerebrovascular disease.
Brain -- Congestion.
Trauma, Nervous System -- diagnosis
Cerebrovascular Disorders
MEDICAL -- Surgery -- General.
Brain -- Congestion
Central nervous system -- Wounds and injuries
Cerebrovascular disease
Form Electronic book
Author Lo, Eng H., editor.
ISBN 9781461486909