Description |
xx, 320 pages, 16 unnumbered pages of plates : illustrations (some color) ; 25 cm |
Series |
Wiley series in probability and statistics |
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Wiley series in probability and statistics.
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Contents |
1. Microarrays in Gene Expression Studies -- 2. Cleaning and Normalization -- 3. Some Cluster Analysis Methods -- 4. Clustering of Tissue Samples -- 5. Screening and Clustering of Genes -- 6. Discriminant Analysis -- 7. Supervised Classification of Tissue Samples -- 8. Linking Microarray Data with Survival Analysis |
Summary |
"Analyzing Microarray Gene Expression Data provides a comprehensive review of available methodologies for the analysis of data derived from the latest DNA microarray technologies. Designed for biostatisticians entering the field of microarray analysis as well as biologists seeking to more effectively analyze their own experimental data, the text features a unique interdisciplinary approach and a combined academic and practical perspective that offers readers the most complete and applied coverage of the subject matter to date."̃ "Following basic overview of the biological and technical principles behind microarray experimentation, the text provides a look at some of the most effective tools and procedures for achieving optimum reliability and reproducibility of research results, including: an in-depth account of the detection of genes that are differentially expressed across a number of classes of tissues; extensive coverage of both cluster analysis and discriminant analysis of microarray data and the growing applications of both methodologies; a model-based approach to cluster analysis, with emphasis on the use of the EMMIX-GENE procedure for the clustering of tissue samples; the latest data cleaning and normalization procedures; and the uses of microarray expression data for providing important prognostic information on the outcome of disease."--BOOK JACKET |
Notes |
Formerly CIP. Uk |
Bibliography |
Includes bibliographical references (pages 267-296) and indexes |
Subject |
DNA microarrays -- Statistical methods.
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Gene expression -- Statistical methods.
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Oligonucleotide Array Sequence Analysis -- methods.
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Gene Expression Profiling -- methods.
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Genre/Form |
Fulltext
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Internet Resources
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Author |
Do, Kim-Anh, 1960-
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Ambroise, Christophe, 1969-
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LC no. |
2004042239 |
ISBN |
9780471226161 hardback |
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0471226165 hardback |
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