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Book Cover
Book
Author McLachlan, Geoffrey J., 1946-

Title Analyzing microarray gene expression data / Geoffrey J. McLachlan, Kim-Anh Do, Christopher Ambroise
Published Hoboken, N.J. : Wiley-Interscience, [2004]
©2004

Copies

Location Call no. Vol. Availability
 W'PONDS  572.8636 Mcl/Amg  AVAILABLE
Description xx, 320 pages, 16 unnumbered pages of plates : illustrations (some color) ; 25 cm
Series Wiley series in probability and statistics
Wiley series in probability and statistics.
Contents 1. Microarrays in Gene Expression Studies -- 2. Cleaning and Normalization -- 3. Some Cluster Analysis Methods -- 4. Clustering of Tissue Samples -- 5. Screening and Clustering of Genes -- 6. Discriminant Analysis -- 7. Supervised Classification of Tissue Samples -- 8. Linking Microarray Data with Survival Analysis
Summary "Analyzing Microarray Gene Expression Data provides a comprehensive review of available methodologies for the analysis of data derived from the latest DNA microarray technologies. Designed for biostatisticians entering the field of microarray analysis as well as biologists seeking to more effectively analyze their own experimental data, the text features a unique interdisciplinary approach and a combined academic and practical perspective that offers readers the most complete and applied coverage of the subject matter to date."̃ "Following basic overview of the biological and technical principles behind microarray experimentation, the text provides a look at some of the most effective tools and procedures for achieving optimum reliability and reproducibility of research results, including: an in-depth account of the detection of genes that are differentially expressed across a number of classes of tissues; extensive coverage of both cluster analysis and discriminant analysis of microarray data and the growing applications of both methodologies; a model-based approach to cluster analysis, with emphasis on the use of the EMMIX-GENE procedure for the clustering of tissue samples; the latest data cleaning and normalization procedures; and the uses of microarray expression data for providing important prognostic information on the outcome of disease."--BOOK JACKET
Notes Formerly CIP. Uk
Bibliography Includes bibliographical references (pages 267-296) and indexes
Subject DNA microarrays -- Statistical methods.
Gene expression -- Statistical methods.
Oligonucleotide Array Sequence Analysis -- methods.
Gene Expression Profiling -- methods.
Genre/Form Fulltext
Internet Resources
Author Do, Kim-Anh, 1960-
Ambroise, Christophe, 1969-
LC no. 2004042239
ISBN 9780471226161 hardback
0471226165 hardback