Preface; Introduction; 1 DNA Chemistry and Biology; 2 A Genome Overview at the Level of Chromosomes; 3 Analysis of DNA Sequences by Hybridization; 4 Polymerase Chain Reaction and Other Methods for In Vitro DNA Amplification; 5 Principles of DNA Electrophoresis; 6 Genetic Analysis; 7 Cytogenetics and Pseudogenetics; 8 Physical Mapping; 9 Enhanced Methods for Physical Mapping; 10 DNA Sequencing: Current Tactics; 11 Strategies for Large-Scale DNA Sequencing; 12 Future DNA Sequencing without Length Fractionation; 13 Finding Genes and Mutations; 14 Sequence-Specific Manipulation of DNA
Summary
A unique exploration of the principles and methods underlying the Human Genome Project and modern molecular genetics and biotechnology-from two top researchers. In Genomics, Charles R. Cantor, former director of the Human Genome Project, and Cassandra L. Smith give the first integral overview of the strategies and technologies behind the Human Genome Project and the field of molecular genetics and biotechnology. Written with a range of readers in mind-from chemists and biologists to computer scientists and engineers-the book begins with a review of the basic properties of DNA and the chromosom
Analysis
genetica
genetics
genomen
genomes
genoomanalyse
genome analysis
mens
man
genexpressieanalyse
genomics
Genome informatics
Genoominformatica
Notes
"Published simultaneously in Canada"--Title page verso
Bibliography
Includes bibliographical references and index
Notes
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL
English
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