| Description |
1 online resource (879 pages) |
| Contents |
Clinical strategies / Bruce Chabner -- Preclinical aspects of cancer drug discovery / Ed Sausville [and others] -- Pharmacokinetics / Jerry Collins -- Infertility / Angela Bradbury, Richard Schilsky -- Carcinogenesis / Larry Blaszkowsky -- Antifolates / Carmen Allegra, Brian Monahan -- 5 fluoropyrimidine / Jean Grem -- Cytidine analogues / David Ryan -- Purine analogues / Kenneth Hande -- Hydroxyurea / Bruce Chabner -- Antimicrotuble agents / Eric Rowinsky -- Alkylating agents/clinical & high dose / Roy Jones, Ken Tew -- Nonclassical agents / Henry Friedman -- Platinum analogues / Ed Reed -- Bleomycin / Bruce Chabner -- Antibiotics / Kees Nooter, Jaap Verweij, Edwin Willems -- Topo I: inhibitors / Alex Sparreboom, William Zamboni -- Topo II: anthracyclines / Jim Doroshow -- Topo II: epipodophylotoxins / Yves Pommier, Francios Goldwasser -- L-asparaginase / Bruce Chabner -- Pharmacology of CNS agents / Jeff Supko -- FDA approval / Thomas Roberts -- Catheter and complications / David Kuter, Rachel Rosovsky -- Pharmacogenetics / Robert Diasio, Jeanne Fourie -- New agents / Louise Grochow -- Bisphosphonates / Matthew Smith -- Thalidomide / Paul Richardson -- Inhibitors of tumor angiogenesis / William Gradishar, Anaadriana Zakarija -- Proteosome inhibitors / Owen O'Connor -- Molecular targeted drugs-growth factor receptor inhibitors / Jeff Clark -- Monoclonal antibody therapies / David Scheinberg -- Interferon / Danield Linder, Earnest Borden -- Adoptive therapies / Carl June -- Vaccines / Glenn Dranoff -- Hematopoietic growth factors / William Petros -- Interleukins / Gheath Alatrash [and others] -- Hormonal therapy for breast cancer and prostate / Peter Lebowitz, Sandra Swain, Steven Balk |
| Summary |
Updated to include the newest drugs and those currently in development, this Fourth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organised by drug class, the book provides the latest information on all drugs and biological agents-their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. The authors explain the rationale for use of drugs in specific schedules and combinations and offer guidelines for dose adjustment in particular situations |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Tumors -- Treatment
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Cancer -- Chemotherapy.
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Cancer -- Immunotherapy.
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Antineoplastic agents.
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Biological response modifiers.
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Neoplasms -- drug therapy
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Biological Factors -- therapeutic use
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Biological Products -- therapeutic use
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Antineoplastic Agents -- therapeutic use
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Immunologic Factors
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Tumors -- Treatment
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Antineoplastic agents
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Biological response modifiers
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Cancer -- Chemotherapy
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Cancer -- Immunotherapy
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Oncolytica.
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Immunotherapie.
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Kanker.
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| Form |
Electronic book
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