Limit search to available items
Book Cover
Author Carey, Michael (Michael F.)

Title Transcriptional regulation in eukaryotes : concepts, strategies, and techniques / Michael Carey, Stephen T. Smale
Published Cold Spring Harbor, NY : Cold Spring Harbor Laboratory Press, [2000]
Online access available from:
ProQuest Ebook Central Subscription    View Resource Record  


Description 1 online resource (xxix, 640 pages) : illustrations
Contents A primer on transcriptional regulation in mammalian cells -- Initial strategic issues -- Modes of regulating mRNA abundance -- Transcription initiation site mapping -- Functional assays for promoter analysis -- Identification and analysis of distant control regions -- Identifying cis-acting DNA elements within a control region -- Identification of DNA-binding proteins and isolation of their genes -- Confirming the functional importance of a protein-DNA interaction -- In vivo analysis of an endogenous control region -- Approaches for the synthesis of recombinant transcription factors -- Identifying and characterizing transcription factor domains -- Theory, characterization, and modeling of DNA binding by regulatory transcription factors -- Crude and fractionated systems for in vitro transcription -- Approaches for studying transcription complex assembly
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Genetic transcription -- Regulations.
Genetic transcription -- Regulations -- Research -- Methodology.
Transcription factors.
Gene Expression Regulation.
Transcription Factors.
Transcription, Genetic.
Genre/Form Rules.
Administrative regulations.
Form Electronic book
Author Smale, Stephen T.
LC no. 99049636
ISBN 0879696656 (electronic bk.)
9780879696658 (electronic bk.)
(alk. paper)
(alk. paper)