| Description |
1 online resource (xvii, 866 pages) : illustrations (some color) |
| Contents |
pt 1. Introduction and Orientation -- Bridges to Life / Ray Kurzweil and Terry Grossman -- Analyzing Predictions: An Anthropological View of Anti-Aging Futures / Courtney Everts Mykytyn -- Towards Naturalistic Transcendence: The Value of Life and Life Extension to Persons as Conative Processes / Steven Horrobin -- The Ethical Basis for Using Human Embryonic Stem Cells in the Treatment of Aging / L. Stephen Coles -- Evolutionary Origins of Aging / Joshua Mitteldorf -- Precedents for the Biological Control of Aging: Experimental Postponement, Prevention, and Reversal of Aging Processes / Gregory M. Fahy -- pt. 2. The Future of Aging -- An Approach to Extending Human Lifespan Today / Christopher B. Heward -- Near Term Prospects for Ameliorating Cardiovascular Aging / Roger Yu, Kaveh Navab and Mohamad Navab -- Near Term Prospects for Broad Spectrum Amelioration of Cancer / Zheng Cui -- Small Molecule Modulators of Sirtuin Activity / Francisco J. Alcaín, Robin K. Minor, José M. Villalba and Rafael de Cabo -- Evolutionary Nutrigenomics / Michael R. Rose, Anthony D. Long, Laurence D. Mueller, Cristina L. Rizza and Kennedy C. Matsagas, et al. -- Biological Effects of Calorie Restriction: Implications for Modification of Human Aging / Stephen R. Spindler -- Calibrating Notch/TGF-[beta] Signaling for Youthful, Healthy Tissue Maintenance and Repair / Morgan Carlson and Irina M. Conboy -- Embryonic Stem Cells: Prospects of Regenerative Medicine for the Treatment of Human Aging / Michael D. West -- Maintenance and Restoration of Immune System Function / Richard Aspinall and Wayne A. Mitchell -- Mitochondrial Manipulation as a Treatment for Aging / Rafal Smigrodzki and Francisco R. Portell -- Life Extension by Tissue and Organ Replacement / Anthony Atala -- Telomeres and the Arithmetic of Human Longevity / Abraham Aviv and John D. Bogden -- Repairing Extracellular Aging and Glycation / John D. Furber -- Methuselah's DNA: Defining Genes That Can Extend Longevity / Robert J. Shmookler Reis and Joan E. McEwen -- Reversing Age-Related DNA Damage Through Engineered DNA Repair / Clifford J. Steer and Betsy T. Kren -- WILT: Necessity, Feasibility, Affordability / Aubrey D.N.J. de Grey -- Comprehensive Nanorobotic Control of Human Morbidity and Aging / Robert A. Freitas |
| Summary |
Just as the health costs of aging threaten to bankrupt developed countries, this book makes the scientific case that a biological "bailout" could be on the way, and that human aging can be different in the future than it is today. Here 40 authors argue how our improving understanding of the biology of aging and selected technologies should enable the successful use of many different and complementary methods for ameliorating aging, and why such interventions are appropriate based on our current historical, anthropological, philosophical, ethical, evolutionary, and biological context. Challenging concepts are presented together with in-depth reviews and paradigm-breaking proposals that collectively illustrate the potential for changing aging as never before. The proposals extend from today to a future many decades from now in which the control of aging may become effectively complete. Examples include sirtuin-modulating pills, new concepts for attacking cardiovascular disease and cancer, mitochondrial rejuvenation, stem cell therapies and regeneration, tissue reconstruction, telomere maintenance, prevention of immunosenescence, extracellular rejuvenation, artificial DNA repair, and full deployment of nanotechnology. The Future of Aging will make you think about aging differently and is a challenge to all of us to open our eyes to the future therapeutic potential of biogerontology |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Aging -- Physiological aspects
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Aging -- Molecular aspects.
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Aging -- Immunological aspects.
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Longevity -- physiology
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MEDICAL -- Physiology.
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SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
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Aging -- Immunological aspects
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Aging -- Molecular aspects
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Aging -- Physiological aspects
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| Form |
Electronic book
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| Author |
Fahy, Gregory M
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| ISBN |
9789048139996 |
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9048139996 |
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